Brănişteanu D, Graur Mariana
Universitatea de Medicină si Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină, Clinica I Oftalmologie.
Rev Med Chir Soc Med Nat Iasi. 2005 Apr-Jun;109(2):230-5.
Diabetic retinopathy is a major cause of blindness worldwide with an expected increasing incidence. Tight blood sugar and blood pressure control have proven essential in preventing both appearance and evolution of retinopathy. Surgical treatments as laser therapy and vitrectomy have also been proved highly effective in preventing major visual loss in advanced stages of retinopathy. Continuous scientific research is leading to a better understanding of pathogenesis of the disease and thus an effective medical treatment is expected in both preventing and treating different stages of diabetic retinopathy. In this update we review ongoing clinical trials and also the knowledge from finalized clinical trials that were testing the clinical impact of experimental treatments or known therapies.
糖尿病性视网膜病变是全球失明的主要原因，且发病率预计会上升。严格控制血糖和血压已被证明对于预防视网膜病变的出现和发展至关重要。手术治疗如激光治疗和玻璃体切除术也已被证明在预防视网膜病变晚期的严重视力丧失方面非常有效。持续的科学研究使人们对该疾病的发病机制有了更好的理解，因此有望开发出一种有效的药物治疗方法来预防和治疗糖尿病性视网膜病变的不同阶段。在本综述中，我们回顾了正在进行的临床试验以及已完成的临床试验的相关知识，这些试验测试了实验性治疗或已知疗法的临床效果。
