Holst-Jensen Arne, De Loose Marc, Van den Eede Guy
National Veterinary Institute, Ullevaalsveien 68, P.O. Box 8156 Dep., 0033 Oslo, Norway.
J Agric Food Chem. 2006 Apr 19;54(8):2799-809. doi: 10.1021/jf052849a.
Analytical methods for the qualitative and quantitative detection of genetically modified (GM) products may serve multiple purposes. Legal requirements differ among jurisdictions, ranging from no requirements to mandatory use of event-specific quantitation and implementation of production chain traceability. Although efforts have been taken to harmonize the analytical methodology at national, regional, and international levels, no normative international standards have yet been established. Lack of coherence between analytical methodologies and their applicabilities, on the one hand, and legislation, on the other hand, is a major problem. Here, key points where coherence is lacking are discussed. These include the definition of units of measurements, expression of GM material quantities, terminology, and inconsistent legal status of products derived from related but slightly different transformation routes. Finally, recommendations to improve the coherence are brought forward, including guidance to stakeholders for prediction of product-specific GM material quantities from gene ratios in the originating seed.
用于定性和定量检测转基因（GM）产品的分析方法可能有多种用途。不同司法管辖区的法律要求各不相同，从无要求到强制使用特定事件定量和实施生产链可追溯性。尽管已在国家、区域和国际层面努力协调分析方法，但尚未建立规范性的国际标准。一方面，分析方法及其适用性与另一方面的立法之间缺乏一致性是一个主要问题。在此，讨论了缺乏一致性的关键点。这些包括测量单位的定义、转基因物质数量的表达、术语以及源自相关但略有不同转化途径的产品不一致的法律地位。最后，提出了提高一致性的建议，包括为利益相关者提供指导，以便根据原始种子中的基因比例预测特定产品的转基因物质数量。
