Xiang H, Han Z, Xie S, Liang Z, Li S, Wang H
Hua Xi Yi Ke Da Xue Xue Bao. 1991 Sep;22(3):329-31.
The study was designed to determine whether the change in the pattern of cervicovaginal peroxidase activity in the fertile period of women can serve as a basis for the development of a technique to predict ovulation time in natural family planning. Eight healthy women volunteered for this study in Chengdu area. The samples of cervical mucus and vaginal secretion were collected. The specific G-Px activity was measured with reference to the procedure of Tsibris, et al., on days 6, 8, 10, 12 through 16, 18, 20, 22, 24 of each menstrual cycle; at the same time an antecubital venous blood sample was drawn to be analyzed for levels of LH, FSH, E2, and P by RIA. The data showed that in 7 ovulatory cycles the G-Px activity did not vary regularly in vaginal secretion but it did drop rapidly in cervical mucus 2 or 3 days before ovulation time and it rose again one day after ovulation. The results suggest that the measurement of the G-Px activity in cervical mucus can be used to predict ovulation by two to three days before the time.
本研究旨在确定女性排卵期宫颈阴道过氧化物酶活性模式的变化是否可作为开发一种预测自然计划生育中排卵时间技术的基础。八名健康女性在成都地区自愿参与本研究。收集宫颈黏液和阴道分泌物样本。按照齐布里斯等人的方法，在每个月经周期的第6、8、10、12至16、18、20、22、24天测量特异性谷胱甘肽过氧化物酶（G-Px）活性；同时抽取肘前静脉血样，通过放射免疫分析法（RIA）分析促黄体生成素（LH）、促卵泡生成素（FSH）、雌二醇（E2）和孕酮（P）的水平。数据显示，在7个排卵周期中，阴道分泌物中的G-Px活性无规律变化，但在排卵前2至3天宫颈黏液中的G-Px活性迅速下降，排卵后一天又再次上升。结果表明，测量宫颈黏液中的G-Px活性可在排卵前两到三天用于预测排卵。
