Schwarz Yehuda, Greif Joel, Becker Heinrich D, Ernst Armin, Mehta Atul
Pulmonary Institute, Tel Aviv Sourasky Medical Center, Weizman Stt 6, Tel Aviv 64239, Israel.
Chest. 2006 Apr;129(4):988-94. doi: 10.1378/chest.129.4.988.
To characterize the feasibility, accuracy, and safety of the superDimension/Bronchus system (SDBS) [superDimension, Ltd; Hertzliya, Israel] in navigating to previously unreachable peripheral lung lesions and obtaining biopsy specimens.
Open-label, prospective, controlled clinical study.
Pulmonary institute of a university-affiliated municipal hospital.
Thirteen adult candidates for nonemergency bronchoscopy who gave informed consent to participate.
The patients underwent flexible bronchoscopy using the SDBS, which is based on real-time CT-guided electromagnetic navigation and is capable of reaching peripheral lung masses beyond the reach of the bronchoscope. A position sensor was used to navigate to and sample the various target lesions for biopsy.
Three-dimensional chest CT was followed by SDBS methodology for marking anatomic landmarks and the target lesion on a virtual bronchoscopy screen and for sampling the lesion. The SDBS assisted in obtaining positive biopsy diagnoses in 9 of 13 cases (69%), with an average navigation accuracy of 5.7 mm. There were no SDBS-related adverse events.
The SDBS is safe and effective in navigating to peripheral lung lesions located beyond the optic limits of a standard flexible bronchoscope.
评估超维度/支气管系统（SDBS）[超维度有限公司；以色列赫兹利亚]在引导至先前无法到达的外周肺病变并获取活检标本方面的可行性、准确性和安全性。
开放标签、前瞻性、对照临床研究。
一所大学附属市级医院的肺科研究所。
13名同意参与的非急诊支气管镜检查成年受试者。
患者接受使用SDBS的柔性支气管镜检查，该系统基于实时CT引导电磁导航，能够到达支气管镜无法触及的外周肺肿块。使用位置传感器引导至各种目标病变并进行活检取样。
三维胸部CT检查后，采用SDBS方法在虚拟支气管镜屏幕上标记解剖标志和目标病变，并对病变进行取样。SDBS在13例中的9例（69%）中协助获得了阳性活检诊断，平均导航精度为5.7毫米。未发生与SDBS相关的不良事件。
SDBS在引导至标准柔性支气管镜视野范围外的外周肺病变方面安全有效。
