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食管溃疡病因的一个有趣原因:IgG κ轻链亚型多发性骨髓瘤。

An interesting cause of esophageal ulcer etiology: Multiple myeloma of IgG kappa subtype.

作者信息

Pehlivan Yavuz, Sevinc Alper, Sari Ibrahim, Gulsen Murat T, Buyukberber Mehmet, Kalender Mehmet E, Camci Celalettin

机构信息

Gaziantep University, School of Medicine, Department of Internal Medicine, Sahinbey Medical Center, Gaziantep, TR-27310, Turkey.

出版信息

World J Gastroenterol. 2006 Apr 14;12(14):2305-7. doi: 10.3748/wjg.v12.i14.2305.

DOI:10.3748/wjg.v12.i14.2305
PMID:16610044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4087669/
Abstract

Multiple myeloma is a neoplasm of mature and immature plasma cells. A 50-year-old woman with lumbago, dysphagia, and left arm pain was presented. Upper endoscopical examination was performed. There was an exudate-covered ulcer in the distal esophagus, located at 30-32 cm from the incisors, covering the whole mucosa. Histopathological examination of the specimens obtained from the lesion showed the involvement of plasma cells consistent with multiple myeloma of IgG kappa subtype. Esophageal involvement of multiple myeloma should be kept in mind in patients presenting with dysphagia.

摘要

多发性骨髓瘤是一种成熟和未成熟浆细胞的肿瘤。本文介绍了一名50岁女性,有腰痛、吞咽困难和左臂疼痛症状。进行了上消化道内镜检查。在距门齿30 - 32厘米处的食管远端有一个被渗出物覆盖的溃疡,累及整个黏膜。对病变部位获取的标本进行组织病理学检查,结果显示浆细胞受累,符合IgG κ亚型的多发性骨髓瘤。对于出现吞咽困难的患者,应考虑多发性骨髓瘤累及食管的情况。

相似文献

1
An interesting cause of esophageal ulcer etiology: Multiple myeloma of IgG kappa subtype.食管溃疡病因的一个有趣原因:IgG κ轻链亚型多发性骨髓瘤。
World J Gastroenterol. 2006 Apr 14;12(14):2305-7. doi: 10.3748/wjg.v12.i14.2305.
2
Simultaneous occurrence of clinical manifestations of myeloma and Waldenström's macroglobulinemia with monoclonal IgG Lambda and IgM Kappa in a single patient.一名患者同时出现骨髓瘤和华氏巨球蛋白血症的临床表现,伴有单克隆IgG λ和IgM κ。
Acta Med Scand. 1981;209(3):229-34. doi: 10.1111/j.0954-6820.1981.tb11582.x.
3
[Normolipemic plane xanthomas and IgG-k multiple myeloma. Description of a clinical case].[血脂正常平面性黄瘤与IgG-κ多发性骨髓瘤。1例临床病例描述]
G Ital Dermatol Venereol. 1990 Oct;125(10):449-51.
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[A case of IgG (k type) multiple myeloma with coma paraproteinemicum and asterixis--hyperviscosity syndrome (author's transl)].一例伴有昏迷性副蛋白血症和扑翼样震颤——高黏滞综合征的IgG(κ型)多发性骨髓瘤(作者译)
Nihon Naika Gakkai Zasshi. 1980 Sep 10;69(9):1119-25.
5
[Human myeloma IgG-kappa half-molecules: a case study (author's transl)].[人骨髓瘤IgG-κ半分子:一项病例研究(作者译)]
Rinsho Ketsueki. 1979 Jul;20(7):762-7.
6
[A case of multiple myeloma with double M-protein peaks for IgG-kappa and IgA-kappa].[一例伴有IgG-κ和IgA-κ双M蛋白峰的多发性骨髓瘤病例]
Rinsho Ketsueki. 1984 Oct;25(10):1646-52.
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Multiple myeloma with serum IgG kappa and Bence Jones lambda biclonal gammopathy.伴有血清IgG κ和本-周蛋白λ双克隆丙种球蛋白病的多发性骨髓瘤
Clin Chem. 1987 Jul;33(7):1305-6.
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[A case of multiple myeloma with two IgG(K) M proteins (author's transl)].一例伴有两种IgG(K)M蛋白的多发性骨髓瘤(作者译)
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[Monoclonal plasmocytic myeloma with 2 paraproteins, IgG kappa and IgG lambdal].伴有两种副蛋白(IgG κ和IgG λ)的单克隆浆细胞骨髓瘤
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Acquired Fanconi syndrome associated with IgG kappa multiple myeloma: observations on the mechanisms of impaired renal acid excretion.与IgG κ轻链多发性骨髓瘤相关的获得性范科尼综合征:关于肾性排酸受损机制的观察
Nephrol Dial Transplant. 1997 Jun;12(6):1251-3. doi: 10.1093/ndt/12.6.1251.

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Occult Esophageal Squamous Cell Carcinoma Presenting with Multiple Bony Osteolytic Lesions Clinically Mimicking Multiple Myeloma: A Diagnostic Dilemma.隐匿性食管鳞状细胞癌伴多发溶骨性骨病变,临床表现酷似多发性骨髓瘤:诊断难题
J Lab Physicians. 2020 Mar;12(1):76-78. doi: 10.1055/s-0040-1714193. Epub 2020 Jul 24.
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Relapse of multiple myeloma presenting as extramedullary plasmacytomas in multiple organs.多发性骨髓瘤复发表现为多器官髓外浆细胞瘤。
Case Rep Hematol. 2015;2015:452305. doi: 10.1155/2015/452305. Epub 2015 Jan 28.

本文引用的文献

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Multiple myeloma.多发性骨髓瘤
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Extramedullary plasmacytoma.髓外浆细胞瘤
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Primary extramedullary plasmacytoma of the esophagus.原发性食管髓外浆细胞瘤
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Gastrointestinal polyposis in multiple myeloma.
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