Ahmed N, Ramos S, Sika J, LeVeen H H, Piccone V A
Cancer. 1976 Aug;38(2):943-7. doi: 10.1002/1097-0142(197608)38:2<943::aid-cncr2820380244>3.0.co;2-b.
Solitary extramedullary plasmacytomas are rare tumors, reported to occur most commonly in the upper respiratory passages, but which also are rarely seen in the middle and lower gastrointestinal system. This report documents the first primary plasmacytoma of the esophagus. A 67-year-old Caucasian man complained of dysphagia and weight loss. Preoperative diagnosis, based on functional inquiry, radiology, and biopsy, was undifferentiated carcinoma involving the lower third of esophagus. The patient was treated by esophagogastrectomy. The pathology specimen revealed the typical histology of plasmacytoma. The extramedullary nature of the tumor was established postoperatively on the basis of the following criteria: 1) Absence of Bence-Jones proteinurea; 2) normal serum electrophoresis; 3) normal bone marrow biopsy; and 4) absence of distant metastases on liver scan and bone survey.
孤立性髓外浆细胞瘤是罕见肿瘤，据报道最常发生于上呼吸道，但在中下胃肠道系统也很少见。本报告记录了首例食管原发性浆细胞瘤。一名67岁的白种男性主诉吞咽困难和体重减轻。基于功能询问、放射学和活检的术前诊断为累及食管下三分之一的未分化癌。患者接受了食管胃切除术。病理标本显示了浆细胞瘤的典型组织学特征。肿瘤的髓外性质在术后根据以下标准确定：1）无本周蛋白尿；2）血清电泳正常；3）骨髓活检正常；4）肝脏扫描和骨检查无远处转移。
