Gomazkov O A, Panfilov A D, Rostovtsev A P, Komissarova N V, Fomin V V, Grigor'iants O O
Vopr Med Khim. 1991 Jul-Aug;37(4):33-7.
Activities of enkephalin- and angiotensin II-forming enzymes (carboxypeptidase H and angiotensin-converting enzyme, ACE) were changed in different brain regions and peripheral tissues of rats with various alcohol motivation. The carboxypeptidase H activity was elevated in midbrain, striatum, hypophysis and adrenal glands, while the ACE activity was increased in hypophysis and striatum. The ACE activity was decreased two-fold in thalamo-hypothalamic region of ethanol-preferring rats.
在具有不同酒精动机的大鼠的不同脑区和外周组织中，脑啡肽生成酶（羧肽酶H）和血管紧张素II生成酶（血管紧张素转换酶，ACE）的活性发生了变化。羧肽酶H的活性在中脑、纹状体、垂体和肾上腺中升高，而ACE的活性在垂体和纹状体中增加。在嗜酒大鼠的丘脑-下丘脑区域，ACE的活性降低了两倍。
