Casas A, Troosters T, Garcia-Aymerich J, Roca J, Hernández C, Alonso A, del Pozo F, de Toledo P, Antó J M, Rodríguez-Roisín R, Decramer M
Servei de Pneumologia, Hospital Clínic, Villarroel 170, Barcelona-08036, Spain.
Eur Respir J. 2006 Jul;28(1):123-30. doi: 10.1183/09031936.06.00063205. Epub 2006 Apr 12.
Hospital admissions due to chronic obstructive pulmonary disease (COPD) exacerbations have a major impact on the disease evolution and costs. The current authors postulated that a simple and well-standardised, low-intensity integrated care intervention can be effective to prevent such hospitalisations. Therefore, 155 exacerbated COPD patients (17% females) were recruited after hospital discharge from centres in Barcelona (Spain) and Leuven (Belgium). They were randomly assigned to either integrated care (IC; n = 65; age mean+/-sd 70+/-9 yrs; forced expiratory volume in one second (FEV(1)) 1.1+/-0.5 L, 43% predicted) or usual care (UC; n = 90; age 72+/-9 yrs; FEV(1) 1.1+/-0.05 L, 41% pred). The IC intervention consisted of an individually tailored care plan upon discharge shared with the primary care team, as well as accessibility to a specialised nurse case manager through a web-based call centre. After 12 months' follow-up, IC showed a lower hospitalisation rate (1.5+/-2.6 versus 2.1+/-3.1) and a higher percentage of patients without re-admissions (49 versus 31%) than UC without differences in mortality (19 versus 16%, respectively). In conclusion, this trial demonstrates that a standardised integrated care intervention, based on shared care arrangements among different levels of the system with support of information technologies, effectively prevents hospitalisations for exacerbations in chronic obstructive pulmonary disease patients.
慢性阻塞性肺疾病(COPD)急性加重导致的住院对疾病进展和费用有重大影响。本文作者推测,一种简单且标准化的低强度综合护理干预措施可能有效预防此类住院情况。因此,从西班牙巴塞罗那和比利时鲁汶的中心招募了155名COPD急性加重患者(17%为女性),这些患者均已出院。他们被随机分为综合护理组(IC;n = 65;年龄均值±标准差70±9岁;一秒用力呼气容积(FEV₁)1.1±0.5升,预计值的43%)或常规护理组(UC;n = 90;年龄72±9岁;FEV₁ 1.1±0.05升,预计值的41%)。IC干预措施包括出院时与初级护理团队共享的个性化护理计划,以及通过基于网络的呼叫中心联系专业护士个案管理员。经过12个月的随访,IC组的住院率较低(1.5±2.6比2.1±3.1),且未再次入院的患者百分比更高(49%比31%),而两组的死亡率无差异(分别为19%和16%)。总之,该试验表明,基于系统不同层面共享护理安排并借助信息技术支持的标准化综合护理干预措施,能有效预防慢性阻塞性肺疾病患者因急性加重而住院。