3T磁共振成像时乳酸测量的陷阱
Pitfalls in lactate measurements at 3T.
作者信息
Lange T, Dydak U, Roberts T P L, Rowley H A, Bjeljac M, Boesiger P
机构信息
Institute for Biomedical Engineering, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland.
出版信息
AJNR Am J Neuroradiol. 2006 Apr;27(4):895-901.
Abstract
In clinical MR spectroscopy at higher field strengths, lactate may show reduced or absent signal intensity at an echo time of 144 ms. Although this false-negative result may be predicted from theory, experimental verification and clinical impact have not been fully established. Using scanners from 3 major vendors, spectra from phantoms and patients demonstrate the lactate signal loss and potential error in interpretation. Strategies are discussed to overcome, or at least alleviate, this problem.
摘要
在更高场强的临床磁共振波谱分析中，乳酸在回波时间为144毫秒时可能显示信号强度降低或消失。尽管这种假阴性结果可从理论上预测，但实验验证和临床影响尚未完全明确。使用来自3家主要供应商的扫描仪，对体模和患者的波谱进行分析，结果显示了乳酸信号缺失以及解释中可能存在的误差。本文讨论了克服或至少减轻这一问题的策略。
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