Canatan Duran, Kose M Rifat, Ustundag Munip, Haznedaroglu Dilek, Ozbas Sema
Department of Pediatric Hematology, National Hemoglobinopathy Council and Suleyman Demirel University, Isparta, Turkey.
Community Genet. 2006;9(2):124-6. doi: 10.1159/000091493.
Hemoglobinopathies are a very important health problem in Turkey. To date many studies have been performed but there has been no national hemoglobinopathy control program (HCP). After the Turkish National Hemoglobinopathy Council (TNHC) was created all centers, foundations, and associations were combined into one organization controlled by the Ministry of Health (MOH). The MOH and the TNHC have started to register the results of the screening of 377,339 healthy subjects from 16 different cities and the recorded average frequency of the beta-thalassemia trait was 4.3%. The highest prevalence of thebeta-thalassemia trait (13.1%) was found in the Antalya region and of the HbS trait (10%) in the Cukurova region. Next, written regulations for the Fight against Hereditary Blood Disease were published especially for preventing and treating hemoglobinopathies. The MOH and the TNHC selected 33 provinces situated in the Thrace, Marmara, Aegean, Mediterranean and South Eastern regions with a high birth prevalence of severe hemoglobinopathies. The hemoglobinopathy scientific committee was set up, a guidebook was published and a national HCP was started in these high-risk provinces.
血红蛋白病在土耳其是一个非常重要的健康问题。迄今为止，已经开展了许多研究，但尚未实施全国性的血红蛋白病控制项目（HCP）。土耳其国家血红蛋白病委员会（TNHC）成立后，所有中心、基金会和协会合并为一个由卫生部（MOH）管控的组织。卫生部和TNHC已开始登记来自16个不同城市的377,339名健康受试者的筛查结果，记录的β地中海贫血特征的平均发生率为4.3%。β地中海贫血特征的最高患病率（13.1%）出现在安塔利亚地区，而镰状细胞血红蛋白（HbS）特征的最高患病率（10%）出现在库库罗瓦地区。接下来，发布了专门用于预防和治疗血红蛋白病的《抗击遗传性血液疾病书面规定》。卫生部和TNHC选择了位于色雷斯、马尔马拉、爱琴海、地中海和东南地区的33个省份，这些地区严重血红蛋白病的出生患病率较高。成立了血红蛋白病科学委员会，发布了一本指南，并在这些高危省份启动了全国性的血红蛋白病控制项目。
