Tam Wing Hung, Yuen Pong Mo, Shan Ng Doris Pui, Leung Pui Ling, Lok Ingrid Hung, Rogers Michael Scott
Department of Obstetrics and Gynecology, The Chinese University of Hong Kong, Hong Kong, SAR, China.
Gynecol Obstet Invest. 2006;62(2):84-8. doi: 10.1159/000092660. Epub 2006 Apr 11.
To compare patients' health status function after treatment with thermal balloon endometrial ablation (TBEA) and levonorgestrel intrauterine system (LNG-IUS) for idiopathic menorrhagia.
Forty-four patients were recruited into a randomized trial comparing their health status after treatment with TBEA or LNG-IUS for idiopathic menorrhagia.
At 1 year follow-up, the mean haemoglobin was significantly higher in women treated with TBEA (12.6 g/dl vs. 10.3 g/dl, p = 0.018). Iron deficiency occurred in 13.3% from the TBEA arm and in 50% from the LNG-IUS arm (p = 0.026). The women's mean Short Form 36 Questionnaire general health perception scores (54.9 vs. 40.5, p = 0.024) and mental health scores (49.5 vs. 38.3, p = 0.021) in TBEA arm were significantly higher than in the LNG-IUS arm. The mental health domain score was also significantly lower in the LNG-IUS arm (46.1 vs. 38.3, p = 0.041).
TBEA appears to offer better health status function at 1 year follow-up and to be more acceptable to our Chinese population in the treatment of idiopathic menorrhagia following failed medical treatment.
比较热球子宫内膜消融术（TBEA）和左炔诺孕酮宫内节育系统（LNG-IUS）治疗特发性月经过多后患者的健康状况功能。
44例患者被纳入一项随机试验，比较TBEA或LNG-IUS治疗特发性月经过多后的健康状况。
在1年随访时，接受TBEA治疗的女性平均血红蛋白水平显著更高（12.6 g/dl对10.3 g/dl，p = 0.018）。TBEA组有13.3%发生缺铁，LNG-IUS组有50%发生缺铁（p = 0.026）。TBEA组女性的简明健康状况调查问卷36项总体健康感知评分（54.9对40.5，p = 0.024）和心理健康评分（49.5对38.3，p = 0.021）显著高于LNG-IUS组。LNG-IUS组的心理健康领域评分也显著更低（46.1对38.3，p = 0.041）。
在1年随访时，TBEA似乎能提供更好的健康状况功能，并且在药物治疗失败的特发性月经过多治疗中，对我国人群更具可接受性。
