Professor Aroldo Fernando Camargos Laboratory of Human Reproduction, Teaching Hospital of the Federal University of Minas Gerais, Minas Gerais, Brazil.
Contraception. 2010 Mar;81(3):226-31. doi: 10.1016/j.contraception.2009.09.012. Epub 2009 Oct 29.
Use of the levonorgestrel-releasing intrauterine system (LNG-IUS) was compared with thermal balloon ablation (TBA) for the treatment of heavy menstrual bleeding (HMB).
A prospective randomized trial comparing the LNG-IUS (n=30 women) and TBA (n=28 women).
Hemoglobin levels increased (p<.001) and blood loss was reduced (p<.001) in both groups after 1 year of treatment. Menstrual bleeding was less in the LNG-IUS group compared to the TBA group at 6 and 12 months of treatment (p=.035 and p=.048, respectively). Intermenstrual bleeding was significantly less in the TBA group at 6 months compared to the LNG-IUS group (p=.044); however, there was no significant difference at 12 months (p=.129). No difference was found in psychological aspects between pre- and posttreatment variables in either of the groups (p=.537).
Both the LNG-IUS and TBA appear to be effective in controlling HMB; however, posttreatment uterine bleeding patterns are different.
左炔诺孕酮宫内节育系统（LNG-IUS）与热球囊消融（TBA）治疗月经过多（HMB）的疗效进行了比较。
前瞻性随机试验比较 LNG-IUS（n=30 名女性）和 TBA（n=28 名女性）。
两组治疗 1 年后血红蛋白水平升高（p<.001），出血量减少（p<.001）。与 TBA 组相比，LNG-IUS 组在治疗 6 个月和 12 个月时的月经出血更少（p=.035 和 p=.048）。与 LNG-IUS 组相比，TBA 组在治疗 6 个月时的间期出血明显更少（p=.044）；然而，12 个月时无显著差异（p=.129）。两组治疗前后的心理方面均无差异（p=.537）。
LNG-IUS 和 TBA 似乎都能有效控制 HMB；然而，治疗后的子宫出血模式不同。
