Zhaori G T, Fu L T, Xu Y H, Guo Y R, Peng Z J, Shan W S
Virology Laboratory, Beijing Pediatric Research Institute.
Chin Med J (Engl). 1991 Oct;104(10):830-3.
Clinical manifestations of respiratory tract infection often precede or coincide with rotavirus gastroenteritis in infants and children. To investigate the possible association between respiratory tract manifestations and rotavirus infection, the authors determined human rotavirus (HRV) antigen and respiratory syncytial virus (RSV) antigen in tracheal aspirates of 58 children with clinically diagnosed pneumonia by enzyme-linked immunosorbent assay (ELISA) and immunofluorescent antibody techniques. HRV antigen was detected in 16 out of the 58 cases (27.6%) and RSV antigen was found positive in 27 cases (46.5%). In four cases both HRV and RSV antigens were detected. The results of our study suggest that rotavirus may occasionally by one of the etiologic agents of acute lower respiratory infections of infants and children and that rotavirus infection may be transmitted via respiratory route. However, further extensive studies are needed for confirmation of the association between rotavirus and respiratory tract infection.
婴幼儿呼吸道感染的临床表现常先于轮状病毒胃肠炎或与之同时出现。为研究呼吸道表现与轮状病毒感染之间的可能关联，作者采用酶联免疫吸附测定（ELISA）和免疫荧光抗体技术，对58例临床诊断为肺炎的儿童气管吸出物中的人轮状病毒（HRV）抗原和呼吸道合胞病毒（RSV）抗原进行了测定。58例中有16例（27.6%）检测到HRV抗原，27例（46.5%）RSV抗原呈阳性。4例同时检测到HRV和RSV抗原。我们的研究结果提示，轮状病毒可能偶尔是婴幼儿急性下呼吸道感染的病原体之一，且轮状病毒感染可能通过呼吸道途径传播。然而，需要进一步广泛研究以证实轮状病毒与呼吸道感染之间的关联。
