Zamora F, Alemany M, Arola L
Department d'Enginyeria Química i Bioquímica, Facultat de Ciències Químiques de Tarragona, Universitat de Barcelona, Tarragona, Spain.
Int J Obes. 1991 Oct;15(10):697-702.
Brown adipose tissue (Na(+)-K+)-ATPase activity, in vitro glucose uptake and 2-aminoisobutyric acid uptake, as well as mitochondrial GDP-binding and succinate dehydrogenase activity were determined in order to study the relationship between these parameters in control, cold acclimated and cafeteria-fed rats. GDP-binding, (Na(+)-K+)-ATPase and glucose uptake were increased in interscapular brown adipose tissue from cold-acclimated and cafeteria-fed rats, whereas 2-aminoisobutyric acid uptake was only increased in cafeteria-fed rats. GDP-binding and (Na(+)-K+)-ATPase activity showed a high correlation coefficient suggesting a parallel modulation of both systems, which would probably share a common regulation mechanism.
为了研究对照、冷适应和喂饲自助饮食大鼠这些参数之间的关系，测定了棕色脂肪组织的（钠钾）-ATP酶活性、体外葡萄糖摄取和2-氨基异丁酸摄取，以及线粒体GDP结合和琥珀酸脱氢酶活性。冷适应和喂饲自助饮食大鼠肩胛间棕色脂肪组织中的GDP结合、（钠钾）-ATP酶和葡萄糖摄取增加，而2-氨基异丁酸摄取仅在喂饲自助饮食大鼠中增加。GDP结合和（钠钾）-ATP酶活性显示出高相关系数，表明这两个系统存在平行调节，这可能共享一种共同的调节机制。
