Kawasaki Tsuneomi, Suzuki Kenta, Shimizu Masako, Ishikawa Keisuke, Soai Kenso
Department of Applied Chemistry, Tokyo University of Science, Tokyo, Japan.
Chirality. 2006 Aug;18(7):479-82. doi: 10.1002/chir.20273.
An enantiomerically enriched pyrimidyl alkanol with either S or R configurations was obtained stochastically from the reaction between pyrimidine-5-carbaldehyde and diisopropylzinc in the presence of achiral silica gel in conjunction with asymmetric autocatalysis with amplification of chirality.
在手性硅胶存在下，嘧啶 - 5 - 甲醛与二异丙基锌反应，通过不对称自催化及手性放大，随机获得了具有S或R构型的对映体富集嘧啶基链烷醇。
