de Pont A C J M
Academisch Medisch Centrum/Universiteit van Amsterdam, afd. Intensive Care Volwassenen, C3-227, Meibergdreef 9, 1105 AZ Amsterdam.
Ned Tijdschr Geneeskd. 2006 Mar 25;150(12):665-9.
The guideline 'Treatment of acute carbon-monoxide poisoning' from doctors in clinics with a tank for hyperbaric ventilation Carbon-monoxide (CO) poisoning is a potentially life-threatening emergency. Its prognosis is determined by prompt recognition and treatment. CO is toxic because it binds to haemoglobin (Hb), thus impairing oxygen transport and causing tissue hypoxia. The most important symptoms are headache and altered consciousness, ranging from somnolence to coma. The diagnosis is based on a history ofCO exposure combined with an elevated carboxyhaemoglobin (HbCO) level in the blood. On the basis of the available literature, it is recommended that patients with a HbCO level > or = 10% should always be treated. In patients requiring artificial ventilation, 100% oxygen for 8 hours is recommended. In pregnant women and in patients who are or have been comatose, hyperbaric oxygen can be considered. In all other symptomatic patients, use of a non-rebreathing mask with 100% oxygen for 8 hours is recommended.
临床医生关于“急性一氧化碳中毒的治疗”的指南:使用高压通风舱进行治疗 一氧化碳(CO)中毒是一种潜在的危及生命的紧急情况。其预后取决于能否迅速识别和治疗。CO具有毒性,因为它会与血红蛋白(Hb)结合,从而损害氧气运输并导致组织缺氧。最重要的症状是头痛和意识改变,从嗜睡到昏迷不等。诊断基于CO暴露史以及血液中碳氧血红蛋白(HbCO)水平升高。根据现有文献,建议HbCO水平≥10%的患者均应接受治疗。对于需要人工通气的患者,建议给予100%氧气8小时。对于孕妇以及当前或曾经昏迷的患者,可以考虑进行高压氧治疗。对于所有其他有症状的患者,建议使用带有100%氧气的非重复呼吸面罩8小时。