Kristoffersen H, Torp-Pedersen S, Terslev L, Qvistgaard E, Holm C Cato, Ellegaard K, Bliddal H
The Parker Institute, Copenhagen University Hospital H:S Frederiksberg Hospital, Copenhagen, Denmark.
Acta Radiol. 2006 Apr;47(3):281-6. doi: 10.1080/02841850600551508.
Ultrasound examination of a group of patients with osteoarthritis (OA) of the knee for signs of inflammation.
71 knees in 71 patients with osteoarthritis of the knee were examined with high-resolution gray-scale ultrasound combined with color and spectral Doppler. The medial, lateral, and antero-superior compartments were examined. Hyperemia was identified as presence of color Doppler signals in the synovial membrane. Low resistance flow was defined as a resistive index < 0.80 on spectral Doppler.
Synovial thickening was found in all knees; fluid in 61 patients; and hyperemia (color Doppler activity) in 51 patients. Of these, 44 had arterial flow on spectral Doppler - 36 with a low resistance flow. When present, fluid and color Doppler activity was found in all three compartments, but with uneven distribution.
The finding in the majority of cases of both effusions on B-mode US and Doppler activity confirms that there is a varying degree of inflammation in knee OA as diagnosed by the ACR criteria.
对一组膝骨关节炎（OA）患者进行超声检查，以查找炎症迹象。
采用高分辨率灰阶超声联合彩色及频谱多普勒对71例膝骨关节炎患者的71个膝关节进行检查。检查内侧、外侧及前上方关节腔。滑膜内出现彩色多普勒信号即为充血。频谱多普勒显示阻力指数<0.80定义为低阻力血流。
所有膝关节均发现滑膜增厚；61例患者有积液；51例患者有充血（彩色多普勒活动）。其中，44例频谱多普勒显示有动脉血流，36例为低阻力血流。出现积液和彩色多普勒活动时，在所有三个关节腔均能发现，但分布不均。
大多数病例中B超显示有积液以及多普勒活动，这证实了按照美国风湿病学会（ACR）标准诊断的膝骨关节炎存在不同程度的炎症。
