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1
Transverse myelitis due to trypanosomiasis in a middle aged Tanzanian man.一名中年坦桑尼亚男子因锥虫病引发横贯性脊髓炎。
J Neurol Neurosurg Psychiatry. 2006 May;77(5):684-5. doi: 10.1136/jnnp.2005.079533.
2
Arsenicals (melarsoprol), pentamidine and suramin in the treatment of human African trypanosomiasis.砷剂(美拉胂醇)、喷他脒和苏拉明用于治疗人类非洲锥虫病。
Parasitol Res. 2003 May;90(1):71-9. doi: 10.1007/s00436-002-0799-9. Epub 2003 Jan 31.
3
Human African trypanosomiasis: potential therapeutic benefits of an alternative suramin and melarsoprol regimen.人类非洲锥虫病:一种替代苏拉明和美拉胂醇疗法的潜在治疗益处。
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Electrocardiographic changes in African trypanosomiasis caused by Trypanosoma brucei rhodesiense.由罗德西亚布氏锥虫引起的非洲锥虫病的心电图变化。
Trans R Soc Trop Med Hyg. 1975;69(4):388-95. doi: 10.1016/0035-9203(75)90194-7.
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Metronidazole and suramin combination in the treatment of arsenical refractory Rhodesian sleeping sickness--a case study.甲硝唑与苏拉明联合治疗对砷剂耐药的罗德西亚昏睡病——病例研究
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Anti-sleeping sickness drugs and cancer chemotherapy.抗昏睡病药物与癌症化疗。
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Chemotherapy of African trypanosomiasis.非洲锥虫病的化学疗法。
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[In vivo resistance to strains of Trypanosoma rhodesiense, Mozambique, 1985].[1985年莫桑比克罗得西亚锥虫株的体内抗性]
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Attempt to correlate urine arsenic excretion with clinical course during melarsoprol therapy of patients with Rhodesian trypanosomiasis.在对罗德西亚锥虫病患者进行美拉胂醇治疗期间,尝试将尿砷排泄与临床病程相关联。
Am J Trop Med Hyg. 1997 Jun;56(6):632-6. doi: 10.4269/ajtmh.1997.56.632.

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Acute transverse myelitis in West Nile Virus, a rare neurological presentation.西尼罗河病毒引起的急性横贯性脊髓炎,一种罕见的神经表现。
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2
Transverse myelitis.横贯性脊髓炎。
Neurol Clin. 2013 Feb;31(1):79-138. doi: 10.1016/j.ncl.2012.09.008.

本文引用的文献

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[Radiological profile in 92 children suffering from Pott's disease].[92例儿童脊柱结核的影像学特征]
Bull Soc Pathol Exot. 2005 Apr;98(1):14-7.
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Computed tomographic evaluation of TB spine in Ibadan.伊巴丹地区脊柱结核的计算机断层扫描评估
West Afr J Med. 2004 Jul-Sep;23(3):228-31. doi: 10.4314/wajm.v23i3.28127.
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The trypanosomiases.锥虫病
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[Changas' myelopathy].[恰加斯脊髓病]
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[Chagasic myelitis].[恰加斯病性脊髓炎]
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Non-compressive myelopathy: clinical and radiological study.非压迫性脊髓病:临床与影像学研究
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Acute transverse myelitis. A localized form of postinfectious encephalomyelitis.
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Paraplegia at the Tikur Anbessa Teaching Hospital: a seven year retrospective study of 164 cases.
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Myelopathies in Ethiopia.埃塞俄比亚的脊髓病
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10
Spinal cord schistosomiasis. A clinical, laboratory and radiological study, with a note on therapeutic aspects.脊髓血吸虫病。一项临床、实验室及影像学研究,并附治疗方面的说明。
Brain. 1991 Apr;114 ( Pt 2):709-26. doi: 10.1093/brain/114.2.709.

一名中年坦桑尼亚男子因锥虫病引发横贯性脊髓炎。

Transverse myelitis due to trypanosomiasis in a middle aged Tanzanian man.

作者信息

Kibiki G S, Murphy D K

机构信息

Department of Internal Medicine, Kilimanjaro Christian Medical Centre, Tumaini University, Moshi, Tanzania.

出版信息

J Neurol Neurosurg Psychiatry. 2006 May;77(5):684-5. doi: 10.1136/jnnp.2005.079533.

DOI:10.1136/jnnp.2005.079533
PMID:16614036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2117437/
Abstract

We report the case of a middle aged Tanzanian man who developed a spinal cord syndrome over 6 weeks, along with a mild encephalopathy. Investigations ruled out the usual major causes of such a syndrome in our setting in northern Tanzania. Examination of his cerebrospinal fluid revealed trypanosomes, and he made a slow but dramatic improvement after a full course of suramine and melarsoprol. We postulate that he had a transverse myelitis due to African trypanosomiasis, a rare and barely recognised cause.

摘要

我们报告了一例中年坦桑尼亚男子的病例,该男子在6周内出现了脊髓综合征,并伴有轻度脑病。调查排除了坦桑尼亚北部我们所在地区此类综合征的常见主要病因。对其脑脊液的检查发现了锥虫,在接受了苏拉明和美拉胂醇的完整疗程后,他虽恢复缓慢但有显著改善。我们推测他患有由非洲锥虫病引起的横贯性脊髓炎,这是一种罕见且鲜为人知的病因。