一名中年坦桑尼亚男子因锥虫病引发横贯性脊髓炎。

Transverse myelitis due to trypanosomiasis in a middle aged Tanzanian man.

作者信息

Kibiki G S, Murphy D K

机构信息

Department of Internal Medicine, Kilimanjaro Christian Medical Centre, Tumaini University, Moshi, Tanzania.

出版信息

J Neurol Neurosurg Psychiatry. 2006 May;77(5):684-5. doi: 10.1136/jnnp.2005.079533.

DOI:10.1136/jnnp.2005.079533

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2117437/

Abstract

We report the case of a middle aged Tanzanian man who developed a spinal cord syndrome over 6 weeks, along with a mild encephalopathy. Investigations ruled out the usual major causes of such a syndrome in our setting in northern Tanzania. Examination of his cerebrospinal fluid revealed trypanosomes, and he made a slow but dramatic improvement after a full course of suramine and melarsoprol. We postulate that he had a transverse myelitis due to African trypanosomiasis, a rare and barely recognised cause.

摘要

我们报告了一例中年坦桑尼亚男子的病例，该男子在6周内出现了脊髓综合征，并伴有轻度脑病。调查排除了坦桑尼亚北部我们所在地区此类综合征的常见主要病因。对其脑脊液的检查发现了锥虫，在接受了苏拉明和美拉胂醇的完整疗程后，他虽恢复缓慢但有显著改善。我们推测他患有由非洲锥虫病引起的横贯性脊髓炎，这是一种罕见且鲜为人知的病因。

相似文献

1

Transverse myelitis due to trypanosomiasis in a middle aged Tanzanian man.一名中年坦桑尼亚男子因锥虫病引发横贯性脊髓炎。

J Neurol Neurosurg Psychiatry. 2006 May;77(5):684-5. doi: 10.1136/jnnp.2005.079533.

2

Arsenicals (melarsoprol), pentamidine and suramin in the treatment of human African trypanosomiasis.砷剂（美拉胂醇）、喷他脒和苏拉明用于治疗人类非洲锥虫病。

Parasitol Res. 2003 May;90(1):71-9. doi: 10.1007/s00436-002-0799-9. Epub 2003 Jan 31.

3

Human African trypanosomiasis: potential therapeutic benefits of an alternative suramin and melarsoprol regimen.人类非洲锥虫病：一种替代苏拉明和美拉胂醇疗法的潜在治疗益处。

Parasitol Int. 2002 Dec;51(4):381-8. doi: 10.1016/s1383-5769(02)00044-2.

4

Electrocardiographic changes in African trypanosomiasis caused by Trypanosoma brucei rhodesiense.由罗德西亚布氏锥虫引起的非洲锥虫病的心电图变化。

Trans R Soc Trop Med Hyg. 1975;69(4):388-95. doi: 10.1016/0035-9203(75)90194-7.

5

Metronidazole and suramin combination in the treatment of arsenical refractory Rhodesian sleeping sickness--a case study.甲硝唑与苏拉明联合治疗对砷剂耐药的罗德西亚昏睡病——病例研究

Trans R Soc Trop Med Hyg. 1996 Jul-Aug;90(4):422. doi: 10.1016/s0035-9203(96)90533-7.

6

Anti-sleeping sickness drugs and cancer chemotherapy.抗昏睡病药物与癌症化疗。

Parasitol Today. 2000 Jan;16(1):7-9. doi: 10.1016/s0169-4758(99)01560-4.

7

Chemotherapy of African trypanosomiasis.非洲锥虫病的化学疗法。

Trop Dis Bull. 1976 Jul;73(7):531-42.

8

[Three patients with African sleeping sickness following a visit to Tanzania].三名曾访问坦桑尼亚的非洲昏睡病患者

Ned Tijdschr Geneeskd. 2002 Dec 28;146(52):2552-6.

9

[In vivo resistance to strains of Trypanosoma rhodesiense, Mozambique, 1985].[1985年莫桑比克罗得西亚锥虫株的体内抗性]

Rev Cubana Med Trop. 1991;43(3):189-93.

10

Attempt to correlate urine arsenic excretion with clinical course during melarsoprol therapy of patients with Rhodesian trypanosomiasis.在对罗德西亚锥虫病患者进行美拉胂醇治疗期间，尝试将尿砷排泄与临床病程相关联。

Am J Trop Med Hyg. 1997 Jun;56(6):632-6. doi: 10.4269/ajtmh.1997.56.632.

引用本文的文献

1

Acute transverse myelitis in West Nile Virus, a rare neurological presentation.西尼罗河病毒引起的急性横贯性脊髓炎，一种罕见的神经表现。

IDCases. 2021 Mar 31;24:e01104. doi: 10.1016/j.idcr.2021.e01104. eCollection 2021.

2

Transverse myelitis.横贯性脊髓炎。

Neurol Clin. 2013 Feb;31(1):79-138. doi: 10.1016/j.ncl.2012.09.008.

本文引用的文献

1

[Radiological profile in 92 children suffering from Pott's disease].[92例儿童脊柱结核的影像学特征]

Bull Soc Pathol Exot. 2005 Apr;98(1):14-7.

2

Computed tomographic evaluation of TB spine in Ibadan.伊巴丹地区脊柱结核的计算机断层扫描评估

West Afr J Med. 2004 Jul-Sep;23(3):228-31. doi: 10.4314/wajm.v23i3.28127.

3

The trypanosomiases.锥虫病

Lancet. 2003 Nov 1;362(9394):1469-80. doi: 10.1016/S0140-6736(03)14694-6.

4

[Changas' myelopathy].[恰加斯脊髓病]

Z Tropenmed Parasitol. 1959 Nov;10:309-14.

5

[Chagasic myelitis].[恰加斯病性脊髓炎]

Rev Fac Cienc Med Cordoba. 1960 Apr-Jun;18:123-7.

6

Non-compressive myelopathy: clinical and radiological study.非压迫性脊髓病：临床与影像学研究

Neurol India. 1999 Dec;47(4):294-9.

7

Acute transverse myelitis. A localized form of postinfectious encephalomyelitis.

Brain. 1997 Jul;120 ( Pt 7):1115-22. doi: 10.1093/brain/120.7.1115.

8

Paraplegia at the Tikur Anbessa Teaching Hospital: a seven year retrospective study of 164 cases.

Ethiop Med J. 1995 Jan;33(1):7-13.

9

Myelopathies in Ethiopia.埃塞俄比亚的脊髓病

East Afr Med J. 1995 Jan;72(1):42-5.

10

Spinal cord schistosomiasis. A clinical, laboratory and radiological study, with a note on therapeutic aspects.脊髓血吸虫病。一项临床、实验室及影像学研究，并附治疗方面的说明。

Brain. 1991 Apr;114 ( Pt 2):709-26. doi: 10.1093/brain/114.2.709.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。