Berczi Viktor, Thomas Steven M, Turner Douglas R, Bottomley John R, Cleveland Trevor J, Gaines Peter A
Sheffield Vascular Institute, Northern General Hospital, Sheffield, United Kingdom.
J Vasc Interv Radiol. 2006 Apr;17(4):645-9. doi: 10.1097/01.RVI.0000203918.91835.73.
Treatment options for acute occlusion of the iliac arteries include surgical thrombectomy, surgical bypass, and endovascular interventions such as thrombolysis and mechanical thrombectomy with or without adjunctive angioplasty or stent implantation. Acute lesions are not usually treated by stent implantation for fear of distal embolism. The purpose of this study was to retrospectively review a single-center experience of primary iliac stent implantation for acute ischemia secondary to acute thrombosis.
Between April 2004 and August 2005, seven patients (five men and two women; mean age, 69.9 y; range, 53-93 y) underwent iliac stent implantation for the acute onset (within 12 days before presentation) of ipsilateral ischemic symptoms. Diagnostic angiography revealed occlusion of the common and external iliac arteries (n = 3) or external iliac artery (n = 4). Patients with rest pain (n = 6) were treated with unfractionated heparin.
All acute occlusions were traversed by the guide wire with relative ease. Recanalization with stent implantation was successful in all cases without distal embolization. Five patients showed noticeable clinical improvement. Two elderly patients with isolated patent profunda segments with no demonstrable distal runoff vessels did not have long-term clinical improvement despite successful iliac recanalization.
This small case series suggests that primary stent implantation for acute iliac occlusions with a patent common femoral artery under intravenous heparin protection may be a reasonable endovascular alternative to thrombolysis for patients who cannot tolerate the time delay to achieve thrombolysis or who have contraindications to thrombolysis. The safety of this technique may be comparable to that of primary stent implantation for chronic occlusions, but larger series would be necessary to confirm this.
髂动脉急性闭塞的治疗选择包括手术取栓、手术搭桥以及血管内介入治疗,如溶栓和机械取栓,可联合或不联合血管成形术或支架植入。由于担心远端栓塞,急性病变通常不采用支架植入治疗。本研究的目的是回顾性分析单中心对急性血栓形成继发急性缺血行原发性髂动脉支架植入的经验。
2004年4月至2005年8月,7例患者(5例男性,2例女性;平均年龄69.9岁;范围53 - 93岁)因同侧缺血症状急性发作(就诊前12天内)接受髂动脉支架植入。诊断性血管造影显示髂总动脉和外髂动脉闭塞(n = 3)或外髂动脉闭塞(n = 4)。有静息痛的患者(n = 6)接受了普通肝素治疗。
所有急性闭塞均较轻松地被导丝穿过。所有病例支架植入再通成功,无远端栓塞。5例患者临床症状明显改善。2例老年患者仅有股深动脉通畅且无明显远端流出道血管,尽管髂动脉再通成功,但未获得长期临床改善。
这个小病例系列表明,对于不能耐受溶栓时间延迟或有溶栓禁忌证的患者,在静脉肝素保护下对股总动脉通畅的急性髂动脉闭塞行原发性支架植入可能是一种合理的血管内替代溶栓的方法。该技术的安全性可能与慢性闭塞原发性支架植入的安全性相当,但需要更大系列的病例来证实这一点。