Davidovici Batya B, Grotto Itamar, Balicer Ran D, Robinson Noah J, Cohen Dani
Department of Epidemiology and Preventive Medicine, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel.
Sex Transm Dis. 2006 Nov;33(11):641-5. doi: 10.1097/01.olq.0000216068.01028.38.
The objective of this study was to estimate the seroprevalence of herpes simplex virus (HSV) types 1 and 2 in male and female soldiers discharged from the Israel Defense Force (IDF) over a period of 18 years.
The goal of this study was to study the secular trends of HSV-1 and HSV-2 infection rates in Israeli young adults.
Three consecutive cross-sectional studies were carried out on stored sera of systematic random samples of soldiers (median age = 20.8) discharged from the IDF in 1984-1985, 1992-1993, and 2001-2002. HSV-1 and -2 seroprevalence was analyzed using indirect IgG enzyme-linked immunosorbent assay for type-specific antibodies.
There was a significant decrease in HSV-1 and HSV-2 seropositivity rates at discharge from the army and an estimated 10-fold decline in the incidence rates of HSV-2 infection during the military service over the last 2 decades.
The decline in HSV-1 seroprevalence rate is similar to that reported from other industrialized countries. The decrease in HSV-2 seroprevalence and transmission rates among Israeli young adults is steeper than that reported from Western countries.
本研究的目的是估计在18年期间从以色列国防军（IDF）退伍的男女士兵中1型和2型单纯疱疹病毒（HSV）的血清阳性率。
本研究的目标是研究以色列年轻人中HSV-1和HSV-2感染率的长期趋势。
对1984 - 1985年、1992 - 1993年和2001 - 2002年从IDF退伍的士兵（中位年龄 = 20.8岁）的系统随机样本的储存血清进行了三项连续的横断面研究。使用间接IgG酶联免疫吸附测定法分析针对型特异性抗体的HSV-1和-2血清阳性率。
退伍时HSV-1和HSV-2血清阳性率显著下降，在过去20年的兵役期间，HSV-2感染发病率估计下降了10倍。
HSV-1血清阳性率的下降与其他工业化国家报告的情况相似。以色列年轻人中HSV-2血清阳性率和传播率的下降比西方国家报告的更为显著。
