Haddow Lewis J, Sullivan Elizabeth A, Taylor Janette, Abel Myriam, Cunningham Anthony L, Tabrizi Sepehr, Mindel Adrian
Sexually Transmitted Infections Research Centre, Westmead, New South Wales, Australia.
Sex Transm Dis. 2007 May;34(5):258-61. doi: 10.1097/01.olq.0000237774.29010.30.
The objective of this study was to estimate the prevalence and correlates of herpes simplex virus type 2 infection in women in an antenatal clinic in the South Pacific island nation of Vanuatu.
A prevalence survey of sexually transmitted infections of pregnant women attending an antenatal clinic at Vila Central Hospital was conducted in 1999-2000. Serum samples were tested for HSV-1 and HSV-2 antibodies by enzyme-linked immunosorbent assay. Results for other sexually transmitted infections and demographic and obstetric variables were analyzed for their association with HSV-2 serostatus.
HSV-2 serum antibody results were obtained on 535 women and HSV-1 results on 134. The seroprevalence of HSV-2 was 30% and HSV-1 was 100%. On multivariate analysis, the independent predictors of HSV-2 infection were age, marital status, and trichomoniasis.
HSV-2 was common in this sample of sexually active women in Vanuatu. This is the first study of HSV in Vanuatu and one of very few studies in the Pacific region.
本研究的目的是估计南太平洋岛国瓦努阿图一家产前诊所中女性单纯疱疹病毒2型感染的患病率及其相关因素。
1999年至2000年，对维拉中心医院产前诊所的孕妇进行了性传播感染患病率调查。通过酶联免疫吸附试验检测血清样本中的HSV-1和HSV-2抗体。分析其他性传播感染的结果以及人口统计学和产科变量与HSV-2血清状态的关联。
获得了535名女性的HSV-2血清抗体结果和134名女性的HSV-1结果。HSV-2的血清阳性率为30%，HSV-1为100%。多因素分析显示，HSV-2感染的独立预测因素为年龄、婚姻状况和滴虫病。
在瓦努阿图的这个性活跃女性样本中，HSV-2感染很常见。这是瓦努阿图首次关于HSV的研究，也是太平洋地区极少数此类研究之一。
