High Whitney A, Miller Misha D
University of Colorado Health Sciences Center, Denver, USA.
MedGenMed. 2005 Nov 3;7(4):33.
Epidermolytic hyperkeratosis (EHK) is a distinct pathologic entity that may present as a generalized congenital disorder. A localized form occurring only upon the female genitalia may not be well appreciated by clinicians dealing with women. EHK of the female genitalia is a rare diagnosis, with just 6 cases reported within the indexed literature. Clinically, it may resemble condyloma, although involvement of human papillomavirus has never been demonstrated. Providers unfamiliar with this entity may be further confused by reports of the histopathologic features. Herein, we describe a case and review the literature with respect to EHK of the female genitalia. Familiarity with this condition is desirable, as confusion with condyloma is likely, yet the prognosis is decidedly different.
表皮松解性角化过度（EHK）是一种独特的病理实体，可表现为全身性先天性疾病。仅发生于女性生殖器的局限性形式可能未被诊治女性患者的临床医生充分认识。女性生殖器EHK是一种罕见的诊断，索引文献中仅报道了6例。临床上，它可能类似尖锐湿疣，尽管从未证实有人乳头瘤病毒感染。不熟悉该实体的医生可能会因组织病理学特征的报告而更加困惑。在此，我们描述一例病例并回顾关于女性生殖器EHK的文献。熟悉这种情况很有必要，因为它很可能被误诊为尖锐湿疣，但其预后明显不同。
