Haldre S J, Kaasik A E, Piirsoo A O
Zh Nevropatol Psikhiatr Im S S Korsakova. 1991;91(7):60-3.
The concentration of cerebral isoenzyme of creatine kinase was measured repeatedly in the cerebrospinal fluid (CSF) in 84 patients with ischemic disorders of brain circulation. Of these, 14 patients presented with transitory ischemic attacks, 20 patients with regressing deficit, and 50 with brain infarction. The patients' health status and functional capacities were estimated on discharge from the hospital. It was discovered that in each patient, the maximum level of cerebral isoenzyme in the CSF was in a good agreement with the clinical course of the disease and neurological status in the survived patients. It may be concluded that measurements of the concentration of the enzyme in the CSF makes it possible to draw more valid prognostic conclusions in patients with ischemic disorders of brain circulation.
对84例脑循环缺血性疾病患者的脑脊液（CSF）中肌酸激酶脑型同工酶的浓度进行了反复测定。其中，14例患者表现为短暂性脑缺血发作，20例患者有缺损症状逐渐消退，50例患者为脑梗死。患者出院时对其健康状况和功能能力进行了评估。结果发现，在每名患者中，脑脊液中脑型同工酶的最高水平与存活患者的疾病临床病程和神经状态高度吻合。可以得出结论，测量脑脊液中该酶的浓度有助于对脑循环缺血性疾病患者得出更有效的预后结论。
