Luh Shi-ping, Yang Pan-chyr
Department of Cardiothoracic Surgery, Taipei Tzu-Chi Medical University Hospital, Taiwan 231, China.
J Zhejiang Univ Sci B. 2006 May;7(5):331-41. doi: 10.1631/jzus.2006.B0331.
Preconditioning (PC) has emerged as a powerful method for experimentally and clinically attenuating various types of organ injuries. In this paper related clinical and basic research issues on organ preconditioning issues were systemically reviewed. Since lung injuries, including ischemia-reperfusion and others, play important roles in many clinical results, including thromboembolism, trauma, thermal injury, hypovolemic and endotoxin shock, reimplantation response after organ transplantation, and many respiratory diseases in critical care. It is of interest to uncover methods, including the PCs, to protect the lung from the above injuries. However, related studies on pulmonary PC are relatively rare and still being developed, so we will review previous literature on experimental and clinical studies on pulmonary PC in the following paragraphs.
预处理（PC）已成为一种在实验和临床中减轻各种器官损伤的有效方法。本文对器官预处理相关的临床和基础研究问题进行了系统综述。由于肺损伤，包括缺血再灌注损伤等，在许多临床病症中起重要作用，如血栓栓塞、创伤、热损伤、低血容量性和内毒素性休克、器官移植后的再植入反应以及重症监护中的许多呼吸系统疾病。因此，探索包括预处理在内的保护肺免受上述损伤的方法具有重要意义。然而，关于肺预处理的相关研究相对较少且仍在不断发展，因此我们将在以下段落中回顾以往关于肺预处理的实验和临床研究文献。
