[儿童偏头痛及其他发作性疾病中的儿茶酚胺]

[Catecholamines in migraine and other paroxysmal conditions in children].

作者信息

Lazebnik T A, Zozuliakova S V, Zalkind L G, Ramina D E

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1991;91(8):6-9.

Abstract

A study was made of the diurnal excretion of adrenaline and noradrenaline in children aged 7 to 14 years suffering from migraine (n = 33), epilepsy (n = 21), and from syncopes (n = 13). For that purpose use was made of fluorometry. The patients with epilepsia and syncopes manifested a fall of adrenaline excretion; noradrenaline excretion correlated with the control data. The children suffering from migraine demonstrated a statistically significant reduction of adrenaline excretion and a rise of noradrenaline excretion, leading to dramatic changes in the amines ratio. Therefore, in patients suffering from vegetovascular dystonia with paroxysmal crises, measurements of adrenaline and noradrenaline excretion may serve an additional criterion for making correct diagnosis.

摘要

对7至14岁患有偏头痛（n = 33）、癫痫（n = 21）和晕厥（n = 13）的儿童进行了肾上腺素和去甲肾上腺素日排泄量的研究。为此采用了荧光测定法。癫痫和晕厥患者表现出肾上腺素排泄量下降；去甲肾上腺素排泄量与对照数据相关。患有偏头痛的儿童肾上腺素排泄量有统计学意义的降低，而去甲肾上腺素排泄量升高，导致胺类比例发生显著变化。因此，对于患有伴有阵发性发作的植物神经功能障碍的患者，测量肾上腺素和去甲肾上腺素排泄量可能作为正确诊断的一项附加标准。