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主动脉肠瘘:不断变化的治疗策略

Aorto-enteric fistula: changing management strategies.

作者信息

Kavanagh D O, Dowdall J F, Younis F, Sheehan S, Mehigan D, Barry M C

机构信息

Dept of Vascular Surgery, St Vincent's University Hospital, Dublin.

出版信息

Ir J Med Sci. 2006 Jan-Mar;175(1):40-4. doi: 10.1007/BF03168999.

DOI:10.1007/BF03168999
PMID:16615228
Abstract

BACKGROUND

Traditionally treatment of aorto-enteric fistulae involved placement of an extra-anatomic bypass and graft excision. This is associated with limb loss (10-40%) and high mortality (10-70%). More recently in situ revascularisation has been advocated.

AIMS

To examine our experience with the changing management of aorto-enteric fistulae over a 22-year period.

METHODS

Demographic, clinical, operative and pathological data were recorded retrospectively.

RESULTS

Twenty-one patients were included. Seven had primary fistulae. Six died prior to intervention. Five had an extra-anatomical bypass (60% mortality, 40% limb loss), four had in-situ revascularisation (25% mortality), four had a primary repair (25% mortality) and two had insertion of a tube graft (primary fistulae). The overall survival rate was 38%. The postoperative survival rate was 6o%.

CONCLUSION

Techniques for operative management continue to evolve. The current trend is towards a local surgical approach with prolonged and intensive postoperative antimicrobial therapy. In our experience this approach has yielded acceptable outcomes.

摘要

背景

传统上,主动脉肠瘘的治疗包括进行解剖外旁路手术和切除移植物。这与肢体丧失(10%-40%)和高死亡率(10%-70%)相关。最近,有人主张进行原位血管重建。

目的

探讨我们在22年期间对主动脉肠瘘治疗方法变化的经验。

方法

回顾性记录人口统计学、临床、手术和病理数据。

结果

纳入21例患者。7例为原发性瘘。6例在干预前死亡。5例行解剖外旁路手术(死亡率60%,肢体丧失率40%),4例行原位血管重建(死亡率25%),4例行一期修复(死亡率25%),2例行管状移植物植入术(原发性瘘)。总体生存率为38%。术后生存率为60%。

结论

手术治疗技术不断发展。当前趋势是采用局部手术方法并进行延长和强化的术后抗菌治疗。根据我们的经验,这种方法产生了可接受的结果。

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Secondary aortoduodenal fistula.继发性主动脉十二指肠瘘
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Vascular prosthetic graft infection: epidemiology, bacteriology, pathogenesis and treatment.血管人工移植物感染:流行病学、细菌学、发病机制及治疗
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In situ replacement of infected aortic grafts with rifampicin-bonded prostheses: the Leicester experience (1992 to 1998).利福平结合型假体原位置换感染性主动脉移植物:莱斯特经验(1992年至1998年)
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