Bergqvist D, Björkman H, Bolin T, Dalman P, Elfström J, Forsberg O, Johansen L, Karacagil S, Karlqvist P A, Länne T, Plate G, Ribbe E, Spangen L, Stenbaek J, Thomsen M, Wiklund B, Angquist K A
Department of Surgery, University Hospital, Uppsala, Sweden.
Eur J Vasc Endovasc Surg. 1996 May;11(4):425-8. doi: 10.1016/s1078-5884(96)80175-4.
To investigate a series of patients with secondary aortoenteric fistulas and compare it with a previous series (1985-93 vs. 1973-84).
Retrospective study of medical records.
Sixteen vascular surgical centers in Sweden.
Twenty-seven patients were identified making an overall incidence of 0.5% of all aortoiliac operations. Among aneurysm patients the incidence was significantly lower than in the previous series. One patient record could not be identified. Fourteen primary operations were for aortic aneurysm, 12 for occlusive disease and one was an aortorenal vein bypass.
Symptoms of the fistula occurred after a median interval of 90 months which is significantly later than the previous series (32 months; p<0.05). The commonest presentation was bleeding followed by septis. The median diagnostic delay was 10.5 days, which was significantly shorter than in the previous series. Most fistulas involved the duodenum (88%). One patient died before surgery. The postoperative mortality was 28%, significantly lower than in the previous series (58%) (p<0.05). At the end of follow up (median 43 months) significantly more patients were alive than in the previous series (42% vs 18%) (p<0.05).
Over a 21 year period there seems to have been a decrease in the frequency of secondary aortoenteric fistulas after aneurysm surgery, a longer interval before they occur, a shorter diagnostic delay, and a better survival.
调查一系列继发性主动脉肠瘘患者,并与之前的系列研究(1985 - 1993年与1973 - 1984年)进行比较。
对病历的回顾性研究。
瑞典的16个血管外科中心。
共确定了27例患者,占所有主髂动脉手术的总发病率为0.5%。在动脉瘤患者中,发病率显著低于之前的系列研究。有一份患者记录无法找到。14例初次手术是针对主动脉瘤,12例是针对闭塞性疾病,1例是主动脉肾静脉搭桥术。
瘘管症状出现的中位间隔时间为90个月,明显晚于之前的系列研究(32个月;p<0.05)。最常见的表现是出血,其次是败血症。中位诊断延迟为10.5天,明显短于之前的系列研究。大多数瘘管累及十二指肠(88%)。1例患者在手术前死亡。术后死亡率为28%,明显低于之前的系列研究(58%)(p<0.05)。在随访结束时(中位43个月),存活的患者明显多于之前的系列研究(42%对18%)(p<0.05)。
在21年的时间里,动脉瘤手术后继发性主动脉肠瘘的发生率似乎有所下降,出现的间隔时间更长,诊断延迟更短,生存率更高。