Making research ethics review work in Zimbabwe--the case for investment in local capacity.

OBJECTIVE

To describe the status of ethics review as pertaining to medical research in Zimbabwe, to compare this with international guidelines, and thus to identify potential improvements in the process.

DESIGN

The description includes background about the national review body, the Medical Research Council of Zimbabwe (MRCZ), and the findings of an analysis of institutional ethics review performed by the MRCZ liaison office.

RESULTS

Discrepancies with international guidelines include application of the concepts of independent and competent review, monitoring of ongoing studies, and ensuring appropriate membership of institutional ethics review committees (IRECs).

CONCLUSION

A focus on research ethics education for researchers and IREC members, as well as ensuring appropriate respect for IREC review, are opportunities for improvement in the process.