Hagens Olivier, Ballabio Andrea, Kalscheuer Vera, Kraehenbuhl Jean-Pierre, Schiaffino M Vittoria, Smith Peter, Staub Olivier, Hildebrand Jeff, Wallingford John B
Dept. of Human Molecular Genetics, Max Planck Institute for Molecular Genetics, Berlin, Germany.
BMC Cell Biol. 2006 Apr 14;7:18. doi: 10.1186/1471-2121-7-18.
Shroom is a recently-described regulator of cell shape changes in the developing nervous system. This protein is a member of a small family of related proteins that are defined by sequence similarity and in most cases by some link to the actin cytoskeleton. At present these proteins are named Shroom, APX, APXL, and KIAA1202. In light of the growing interest in this family of proteins, we propose here a new standard nomenclature.
Shroom是一种最近被描述的在发育中的神经系统中调节细胞形状变化的因子。该蛋白是一个相关蛋白小家族的成员，这些蛋白通过序列相似性定义，并且在大多数情况下与肌动蛋白细胞骨架存在某种联系。目前，这些蛋白被命名为Shroom、APX、APXL和KIAA1202。鉴于对该蛋白家族的兴趣日益增加，我们在此提出一种新的标准命名法。
