Mattevi Andrea
Structure. 2006 Apr;14(4):628-9. doi: 10.1016/j.str.2006.03.002.
Carnitine palmitoyltransferases (CPTs) are part of the enzymatic system that imports fatty acids into mitochondria. The crystal structure of rat CPT-2 by Rufer et al. (2006) (this issue of Structure) reveals a Y-shaped tunnel for binding the CoA and acyl-carnitine substrates and a hydrophobic insert mediating membrane association.
肉碱棕榈酰转移酶（CPTs）是将脂肪酸导入线粒体的酶系统的一部分。鲁弗等人（2006年，本期《结构》杂志）解析的大鼠CPT-2晶体结构显示，其存在一个用于结合辅酶A和酰基肉碱底物的Y形通道以及一个介导膜结合的疏水插入片段。
