Buffington C A Tony, Westropp Jodi L, Chew Dennis J, Bolus Roger R
Department of Veterinary Clinical Sciences, The Ohio State University Veterinary Hospital, 601 Vernon L. Tharp Street, Columbus, OH 43210-1089, USA.
J Feline Med Surg. 2006 Aug;8(4):261-8. doi: 10.1016/j.jfms.2006.02.002. Epub 2006 Apr 17.
This prospective observational study evaluated client-reported recurrence of lower urinary tract signs (LUTS) and other signs of abnormalities in cats with idiopathic cystitis after institution of multimodal environmental modification (MEMO). Forty-six client-owned indoor-housed cats with idiopathic cystitis, diagnosed based on a history of recurrent LUTS and evidence of absence of urolithiasis or bacterial urinary tract infection were studied. In addition to their usual care, clients were offered recommendations for MEMO based on a detailed environmental history. Cases were followed for 10 months by client contact to determine the effect of MEMO on LUTS and other signs. Significant (P<0.05) reductions in LUTS, fearfulness, nervousness, signs referable to the respiratory tract, and a trend (P<0.1) toward reduced aggressive behavior and signs referable to the lower intestinal tract were identified. These results suggest that MEMO is a promising adjunctive therapy for indoor-housed cats with LUTS, and should be followed up with prospective controlled clinical trials.
这项前瞻性观察性研究评估了在采取多模式环境改良（MEMO）措施后，特发性膀胱炎猫主人报告的下尿路症状（LUTS）复发情况及其他异常体征。研究对象为46只家养室内猫，这些猫被诊断为特发性膀胱炎，诊断依据是有复发性LUTS病史且无尿石症或细菌性尿路感染的证据。除了常规护理外，根据详细的环境病史为猫主人提供MEMO建议。通过与猫主人联系对病例进行了10个月的随访，以确定MEMO对LUTS及其他体征的影响。结果发现，LUTS、恐惧、紧张、呼吸道相关体征显著减少（P<0.05），攻击行为和下肠道相关体征有减少趋势（P<0.1）。这些结果表明，MEMO对于有LUTS的家养室内猫是一种有前景的辅助治疗方法，应通过前瞻性对照临床试验进行后续研究。
