Bouldin Marshall J, Ross Leigh Ann, Sumrall Caryl D, Loustalot Fleetwood V, Low Annette K, Land Kelly K
University of Mississippi Medical Center, Jackson, Mississippi 39216, USA.
Am J Med Sci. 2006 Apr;331(4):183-93. doi: 10.1097/00000441-200604000-00004.
Obesity is epidemic in the modern world. It is becoming increasingly clear that obesity is a major cause of cardiovascular disease, diabetes, and renal disease, as well as a host of other comorbidities. There are at present no generally effective long-term medical therapies for obesity. Surgical therapy for morbid obesity is not only effective in producing long-term weight loss but is also effective in ameliorating or resolving several of the most significant complications of obesity, including diabetes, hypertension, dyslipidemia, sleep apnea, gastroesophageal reflux disease, degenerative joint disease, venous stasis, pseudotumor cerebri, nonalcoholic steatohepatitis, urinary incontinence, fertility problems, and others. The degree of benefit and the rates of morbidity and mortality of the various surgical procedures vary according to the procedure.
肥胖在现代世界呈流行趋势。越来越明显的是,肥胖是心血管疾病、糖尿病和肾脏疾病以及许多其他合并症的主要原因。目前尚无普遍有效的肥胖长期医学治疗方法。病态肥胖的手术治疗不仅能有效实现长期体重减轻,还能有效改善或解决肥胖的一些最严重并发症,包括糖尿病、高血压、血脂异常、睡眠呼吸暂停、胃食管反流病、退行性关节病、静脉淤滞、假性脑瘤、非酒精性脂肪性肝炎、尿失禁、生育问题等。各种手术程序的受益程度以及发病率和死亡率因程序而异。