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腹腔镜垂直袖状胃切除术:一项退伍军人事务部的5年回顾

Laparoscopic vertical sleeve gastrectomy: A 5-year veterans affairs review.

作者信息

Barry Rahman G, Amiri Farzad A, Gress Todd W, Nease D Blaine, Canterbury Timothy D

机构信息

Department of Surgery, Marshall University Department of Surgery, Huntington Veterans Affairs Medical Center, Huntington, WV.

出版信息

Medicine (Baltimore). 2017 Sep;96(35):e7508. doi: 10.1097/MD.0000000000007508.

Abstract

The aim of this study was to evaluate the outcomes after laparoscopic sleeve gastrectomy (SG) in a VA population.SG has recently gained popularity as a definitive bariatric surgery procedure. Data are lacking on long-term outcomes, particularly in a Veterans Affairs population.We retrospectively reviewed 223 patients who underwent SG for morbid obesity between January 2009 and June 2014. Data on length of stay, complications, interval weight loss, comorbidities, and number of therapies preoperatively and at long-term follow-up were collected.There were 164 males and 59 females who underwent SG. The mean body mass index was 45.4 kg/m. Mean excess weight loss at 1 year was 62.9%, and 47.0% at 5 years. Weight loss continued until 12 to 18 months, when there was a nadir in weight loss (P < .001). There were 4 deaths and 4 staple-line leaks, with 3 deaths related to late cardiac events. One early death occurred in a very high-risk patient. All staple-line leaks were managed nonoperatively. Of the 223 patients, 193 had hypertension, 137 diabetes, 158 hyperlipidemia, 119 obstructive sleep apnea (OSA), and 125 had gastroesophageal reflux disease. Preoperatively, patients were on a mean of 1.9 antihypertensive and 0.9 hyperlipidemic, anti-reflux and oral hypoglycemic agents. Fifty percent of patients with diabetes were on insulin and 68% with OSA used continuous positive airway pressure/bilevel positive airway pressure (CPAP/BiPAP). We found significant absolute reductions in mean antihypertensive medications (-0.8), hyperlipidemic agents (-0.4), antireflux agents (-0.4), oral hypoglycemics (-0.6), insulin use (-25%), and use of CPAP/BiPAP (-55%) (all P < .001).Laparoscopic sleeve gastrectomy is a safe and effective bariatric surgery procedure, resulting in significant early weight loss up to 18 months and long-term improvement in all major obesity-related comorbid conditions.

摘要

本研究的目的是评估退伍军人事务部(VA)人群接受腹腔镜袖状胃切除术(SG)后的结果。SG作为一种确定性减肥手术程序,最近越来越受欢迎。目前缺乏关于长期结果的数据,尤其是在退伍军人事务部人群中。我们回顾性分析了2009年1月至2014年6月期间因病态肥胖接受SG的223例患者。收集了住院时间、并发症、体重减轻情况、合并症以及术前和长期随访时的治疗次数等数据。

接受SG的患者中有164名男性和59名女性。平均体重指数为45.4kg/m²。1年时平均超重减轻率为62.9%,5年时为47.0%。体重减轻持续到12至18个月,此时体重减轻出现最低点(P<0.001)。有4例死亡和4例吻合口漏,3例死亡与晚期心脏事件有关。1例早期死亡发生在一名极高风险患者身上。所有吻合口漏均采用非手术治疗。在223例患者中,193例患有高血压,137例患有糖尿病,158例患有高脂血症,119例患有阻塞性睡眠呼吸暂停(OSA),125例患有胃食管反流病。术前,患者平均服用1.9种抗高血压药物和0.9种降血脂、抗反流及口服降糖药物。50%的糖尿病患者使用胰岛素,68%的OSA患者使用持续气道正压通气/双水平气道正压通气(CPAP/BiPAP)。我们发现抗高血压药物(-0.8)、降血脂药物(-0.4)、抗反流药物(-0.4)、口服降糖药物(-0.6)、胰岛素使用量(-25%)以及CPAP/BiPAP使用量(-55%)均有显著绝对减少(所有P<0.001)。

腹腔镜袖状胃切除术是一种安全有效的减肥手术程序,可在18个月内实现显著的早期体重减轻,并使所有主要肥胖相关合并症得到长期改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a66/5585473/348fdf9b0285/medi-96-e7508-g001.jpg

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