Second Department of Endocrinology, Alexandra General Hospital, Athens, Greece.
Hormones (Athens). 2012 Jul-Sep;11(3):233-40. doi: 10.14310/horm.2002.1353.
Obesity both in adults and children has emerged as a worldwide epidemic. Obesity is associated with an increased risk of a number of comorbidities including type 2 diabetes mellitus, hypertension, dyslipidemia, obstructive sleep apnea, certain types of cancer, degenerative joint disease, non-alcoholic fatty liver disease, reflux esophagitis, stroke, coronary heart disease, venous stasis ulcers, cholelithiasis, erectile dysfunction and polycystic ovary syndrome. It is now generally accepted that bariatric surgery procedures induce long-term weight loss and offer resolution or dramatic improvement in numerous comorbidities of obesity, including type 2 diabetes mellitus, hypertension and dyslipidemia. These effects mainly arise from endocrine changes resulting from the gastrointestinal surgical procedures. The aim of this short review was to evaluate the pros and cons of bariatric surgery for morbid obesity seen from the perspective of a practicing endocrinologist.
肥胖症无论是在成人还是儿童中都已成为一种全球性的流行疾病。肥胖症与多种合并症的风险增加有关，包括 2 型糖尿病、高血压、血脂异常、阻塞性睡眠呼吸暂停、某些类型的癌症、退行性关节疾病、非酒精性脂肪性肝病、胃食管反流病、中风、冠心病、静脉淤滞性溃疡、胆石症、勃起功能障碍和多囊卵巢综合征。现在普遍认为，减重手术程序可诱导长期体重减轻，并解决或显著改善肥胖症的多种合并症，包括 2 型糖尿病、高血压和血脂异常。这些影响主要源于胃肠手术引起的内分泌变化。本综述的目的是从内分泌学家的角度评估病态肥胖症的减重手术的利弊。
