Gundy Sarolta
Diagnosztikus Onkocytogenetikai Osztály, Országos Onkológiai Intézet, Budapest 1122, Hungary.
Magy Onkol. 2006;50(1):5-18. Epub 2006 Apr 17.
The author deals with the effects of environmental chemical-, and physical carcinogens playing predominant role in nearly 90% of the cancer development. Different steps of chemical carcinogenesis, classification and evaluation of carcinogens according to the criteria of International Agency for Research on Cancer, and the most important biological markers of genotoxic exposures are presented. Among physical agents the carcinogenic effects of ionizing and nonionizing radiations are demonstrated, including limited, inadequate or proved carcinogenic action of UV, microwave, static and low-frequency electric and magnetic fields.
作者探讨了环境化学致癌物和物理致癌物在近90%的癌症发生过程中所起的主要作用。介绍了化学致癌作用的不同阶段、根据国际癌症研究机构的标准对致癌物进行的分类和评估，以及遗传毒性暴露的最重要生物标志物。在物理因素中，展示了电离辐射和非电离辐射的致癌作用，包括紫外线、微波、静电和低频电场的致癌作用有限、证据不足或已被证实。
