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干细胞移植、化疗及放疗后霍奇金淋巴瘤相关的治疗性脊髓炎:一例病例报告及文献综述

Treatment related myelitis in Hodgkin's lymphoma following stem cell transplant, chemotherapy and radiation: a case report and review of the literature.

作者信息

Gatcombe Heather, Lawson Josh, Phuphanich Surasak, Crocker Ian

机构信息

Department of Radiation-Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA.

出版信息

J Neurooncol. 2006 Sep;79(3):293-8. doi: 10.1007/s11060-006-9140-2. Epub 2006 Apr 15.

DOI:10.1007/s11060-006-9140-2
PMID:16617406
Abstract

Radiation myelitis, while rare, is one of the most devastating complications of radiation treatment. We report here a case of a 25-year-old Middle Eastern man with progressive myelopathy 21 months following low dose irradiation of the cord in the context of high dose chemotherapy and stem cell rescue and a review of the literature.

摘要

放射性脊髓炎虽罕见,但却是放射治疗最严重的并发症之一。我们在此报告一例25岁中东男性病例,该患者在高剂量化疗及干细胞救援过程中接受脊髓低剂量照射后21个月出现进行性脊髓病,并对相关文献进行综述。

相似文献

1
Treatment related myelitis in Hodgkin's lymphoma following stem cell transplant, chemotherapy and radiation: a case report and review of the literature.干细胞移植、化疗及放疗后霍奇金淋巴瘤相关的治疗性脊髓炎:一例病例报告及文献综述
J Neurooncol. 2006 Sep;79(3):293-8. doi: 10.1007/s11060-006-9140-2. Epub 2006 Apr 15.
2
Radiation myelitis following allogeneic stem cell transplantation and consolidation radiotherapy for non-Hodgkin's lymphoma.异基因干细胞移植及巩固放疗治疗非霍奇金淋巴瘤后发生的放射性脊髓炎。
Bone Marrow Transplant. 2000 Dec;26(12):1355-9. doi: 10.1038/sj.bmt.1702705.
3
[Post-radiotherapy myelopathies during Hodgkin's disease. Apropos of 4 cases].
Rev Neurol (Paris). 1970 Dec;123(6):369-86.
4
Relationship between curative radiation therapy of paravertebral tumors and the incidence of radiation myelitis.
Tumori. 1978 Jun 30;64(3):305-12. doi: 10.1177/030089167806400308.
5
Phase I study of involved-field radiotherapy preceding autologous stem cell transplantation for patients with high-risk lymphoma or Hodgkin's disease.高危淋巴瘤或霍奇金病患者自体干细胞移植前受累野放疗的I期研究。
Int J Radiat Oncol Biol Phys. 2004 May 1;59(1):208-18. doi: 10.1016/j.ijrobp.2003.07.004.
6
[Radiation-induced myelitis following accelerated radiotherapy].[加速放疗后放射性脊髓炎]
Strahlenther Onkol. 1993 Sep;169(9):543-4.
7
Meningeal hematopoiesis following radiation myelitis in a hematopoietic stem-cell transplant recipient.造血干细胞移植受者放射性脊髓炎后的脑膜造血
Am J Hematol. 2005 Aug;79(4):291-3. doi: 10.1002/ajh.20341.
8
Refractory or relapsed Hodgkin's disease and non-Hodgkin's lymphoma: optimizing involved-field radiotherapy in transplant patients.难治性或复发性霍奇金淋巴瘤和非霍奇金淋巴瘤:优化移植患者的累及野放疗
Cancer J. 2005 Sep-Oct;11(5):425-31. doi: 10.1097/00130404-200509000-00011.
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Spinal cord response to altered fractionation and re-irradiation: radiobiological considerations and role of bioeffect models.脊髓对分割方式改变和再照射的反应:放射生物学考量及生物效应模型的作用
J Cancer Res Ther. 2006 Jul-Sep;2(3):105-18. doi: 10.4103/0973-1482.27597.
10
Radiation myelitis: a complication of concurrent cisplatin and 5-fluorouracil chemotherapy with extended field radiotherapy for carcinoma of the uterine cervix.
Gynecol Oncol. 1991 Dec;43(3):305-8. doi: 10.1016/0090-8258(91)90041-3.

引用本文的文献

1
Extranodal classical Hodgkin lymphoma involving the spinal cord: case report and review of the literature.结外经典型霍奇金淋巴瘤累及脊髓:病例报告及文献复习。
CNS Oncol. 2022 Sep 1;11(3):CNS88. doi: 10.2217/cns-2021-0011. Epub 2022 Jun 13.

本文引用的文献

1
Normal-tissue toxicities of thoracic radiation therapy: esophagus, lung, and spinal cord as organs at risk.
Hematol Oncol Clin North Am. 2004 Feb;18(1):131-60, x-xi. doi: 10.1016/s0889-8588(03)00150-3.
2
A review on radiogenic Lhermitte's sign.放射性莱尔米特征综述。
Pathol Oncol Res. 2003;9(2):115-20. doi: 10.1007/BF03033755. Epub 2003 Jul 14.
3
Brief report: chronic myelopathy after combined chemo-radiotherapy in a patient with relapsed mediastinal B-cell lymphoma.简短报告:一名复发性纵隔B细胞淋巴瘤患者在放化疗联合治疗后出现慢性脊髓病。
Med Pediatr Oncol. 2002 Jun;38(6):442-4. doi: 10.1002/mpo.1360.
4
Pathology of radiation myelopathy.放射性脊髓病的病理学
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[Chronic progressive radiation myelopathy after bone marrow transplantation].
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Radiation myelopathy following transplantation and radiotherapy for non-Hodgkin's lymphoma.非霍奇金淋巴瘤移植及放疗后放射性脊髓病
Int J Radiat Oncol Biol Phys. 1998 Jul 15;41(5):1057-61. doi: 10.1016/s0360-3016(98)00107-2.
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Radiation response of the central nervous system.中枢神经系统的辐射反应。
Int J Radiat Oncol Biol Phys. 1995 Mar 30;31(5):1093-112. doi: 10.1016/0360-3016(94)00655-5.
8
The incidence of myelitis after irradiation of the cervical spinal cord.颈段脊髓照射后脊髓炎的发病率。
Int J Radiat Oncol Biol Phys. 1990 Jul;19(1):3-8. doi: 10.1016/0360-3016(90)90126-5.
9
Spinal cord radiation "tolerance": doctrine versus data.脊髓放疗“耐受性”:理论与数据
Int J Radiat Oncol Biol Phys. 1990 Jul;19(1):219-21. doi: 10.1016/0360-3016(90)90157-f.
10
Invited review: permanent radiation myelopathy.
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