Ho A M H, Chung D C, Karmakar M K, Gomersall C D, Peng Z, Tay B A
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong S.A.R., P R C.
Anaesth Intensive Care. 2006 Apr;34(2):211-5. doi: 10.1177/0310057X0603400207.
This prospective before-and-after observational study investigated the effect of upper airway anaesthesia on dynamic airflow. Six consenting ASA 1 adults, all authors of this study, underwent a series of spirometric measurements before and after topical anaesthesia of the upper airway using lignocaine. Peak inspiratory flow rate, forced inspiratory flow between 25% and 75% of the maximum inhaled volume, forced expiratory volume at 1 second, and forced vital capacity in the supine and sitting positions were measured. The measured inspiratory parameters were significantly reduced after lignocaine topical anaesthesia of the upper airway. Expiratory flow parameters were not affected. We conclude that topical anaesthesia of the upper airway leads to dynamic inspiratory airflow limitation.
这项前瞻性前后对照观察性研究调查了上气道麻醉对动态气流的影响。六名自愿参与的美国麻醉医师协会(ASA)1级成年患者(均为本文作者)在使用利多卡因对上气道进行局部麻醉前后接受了一系列肺活量测定。测量了仰卧位和坐位时的吸气峰值流速、最大吸入量的25%至75%之间的用力吸气流速、1秒用力呼气量和用力肺活量。上气道利多卡因局部麻醉后,所测吸气参数显著降低。呼气流量参数未受影响。我们得出结论,上气道局部麻醉会导致动态吸气气流受限。