Smeets Rob J E M, Vlaeyen Johan W S, Kester Arnold D M, Knottnerus J André
Rehabilitation Centre Blixembosch, Eindhoven, The Netherlands.
J Pain. 2006 Apr;7(4):261-71. doi: 10.1016/j.jpain.2005.10.011.
The aim of this study was to examine whether treatments based on different theories change pain catastrophizing and internal control of pain, and whether changes in these factors mediate treatment outcome. Participants were 211 patients with nonspecific chronic low back pain (CLBP) participating in a randomized controlled trial, attending active physical treatment (APT, n = 52), cognitive-behavioral treatment (CBT, n = 55), treatment combining the APT and CBT (CT, n = 55), or waiting list (WL, n = 49). Pain catastrophizing decreased in all 3 active treatment groups and not in the WL. There was no difference in the change in internal control across all 4 groups. In all the active treatment groups, patients improved regarding perceived disability, main complaints, and current pain at post-treatment, and no changes were observed in the WL group. Depression only changed significantly in the APT group. Change in pain catastrophizing mediated the reduction of disability, main complaints, and pain intensity. In the APT condition, pain catastrophizing also mediated the reduction of depression. Not only cognitive-behavioral treatments but also a physical treatment produced changes in pain catastrophizing that seemed to mediate the outcome of the treatment significantly. The implications and limitations of these results are discussed.
This article shows that treatment elements that do not deliberately target cognitive factors can reduce pain catastrophizing. Reduction in pain catastrophizing seemed to mediate the improvement of functioning in patients with chronic low back pain. The results might contribute to the development of more effective interventions.
本研究的目的是检验基于不同理论的治疗方法是否会改变疼痛灾难化和疼痛的内部控制,以及这些因素的变化是否介导治疗结果。研究参与者为211名非特异性慢性下腰痛(CLBP)患者,他们参与了一项随机对照试验,分别接受主动物理治疗(APT,n = 52)、认知行为治疗(CBT,n = 55)、APT与CBT相结合的治疗(CT,n = 55)或等待列表(WL,n = 49)。所有3个主动治疗组的疼痛灾难化程度均降低,而WL组未降低。所有4组的内部控制变化无差异。在所有主动治疗组中,患者在治疗后关于感知到的残疾、主要症状和当前疼痛方面均有改善,而WL组未观察到变化。仅APT组的抑郁有显著变化。疼痛灾难化的变化介导了残疾、主要症状和疼痛强度的降低。在APT治疗条件下,疼痛灾难化还介导了抑郁的降低。不仅认知行为治疗,而且物理治疗也会使疼痛灾难化产生变化,这似乎显著介导了治疗结果。讨论了这些结果的意义和局限性。
本文表明,并非刻意针对认知因素的治疗要素也可降低疼痛灾难化。疼痛灾难化的降低似乎介导了慢性下腰痛患者功能的改善。这些结果可能有助于开发更有效的干预措施。