Barros D'Sa A A B, Harkin D W, Blair P H B, Hood J M, McIlrath E
Regional Vascular Surgery Unit, The Royal Victoria Hospital, Belfast, UK.
Eur J Vasc Endovasc Surg. 2006 Sep;32(3):246-56. doi: 10.1016/j.ejvs.2006.02.004. Epub 2006 Apr 18.
Complex lower limb vascular injuries (CLVIs) in high-energy penetrating or blunt trauma are associated with an unacceptably high incidence of complications including amputation. Traumatic ischaemia and ischaemia-reperfusion injury (IRI) of skeletal muscle often lead to limb loss, the systemic inflammatory response syndrome (SIRS) which affects remote organs and even the potentially fatal multiple organ dysfunction syndrome (MODS). Surgical care of CLVIs everywhere, including Northern Ireland until 1978, was governed by an anxiety to restore arterial flow quickly often using expedient and flawed repair techniques while a damaged major vein was frequently ligated.
A new policy centred on early intraluminal shunting of both artery and vein, restoring arterial inflow and venous outflow, respectively, was introduced at the Regional Vascular Surgery Unit of The Royal Victoria Hospital, Belfast in 1979. It imposed a disciplined one-stage comprehensive approach to treatment involving a sequence of operative manoeuvres in which all damaged anatomical elements receive meticulous and optimal attention unshackled by time constraints.
Comparisons drawn between the pre-shunt period of unplanned treatment (1969-1978) and the post-shunt period centred on the use of shunts (1979-2000) showed that early shunting of both artery and vein in both penetrating (P) and blunt (B) injuries significantly reduced the necessity for fasciotomy (P: p=0.016, B: p=0.02) and caused a significant fall in the incidence of contracture (P: p=0.018, B: p=0.02) and of amputation (P: p=0.009, P: p=0.012).
The policy of early shunting of artery and vein in CLVIs has proved to be of great benefit in terms of significantly improved outcomes, better operative discipline and harmonious collaboration among the specialists involved.
高能穿透性或钝性创伤导致的复杂下肢血管损伤(CLVI),其并发症(包括截肢)的发生率高得令人难以接受。骨骼肌的创伤性缺血和缺血再灌注损伤(IRI)常导致肢体丧失、影响远处器官的全身炎症反应综合征(SIRS),甚至可能致命的多器官功能障碍综合征(MODS)。直到1978年,包括北爱尔兰在内的各地对CLVI的外科治疗,都因急于迅速恢复动脉血流而受到影响,常采用权宜且有缺陷的修复技术,同时受损的大静脉常被结扎。
1979年,贝尔法斯特皇家维多利亚医院区域血管外科引入了一项新政策,该政策以动脉和静脉的早期腔内分流为中心,分别恢复动脉流入和静脉流出。它采用了一种严谨的一期综合治疗方法,包括一系列手术操作,在此过程中,所有受损的解剖结构都能在不受时间限制的情况下得到细致且最佳的处理。
对计划外治疗的分流前时期(1969 - 1978年)和以分流使用为中心的分流后时期(1979 - 2000年)进行比较,结果显示,在穿透伤(P)和钝性伤(B)中,动脉和静脉的早期分流均显著降低了筋膜切开术的必要性(P:p = 0.016,B:p = 0.02),并使挛缩发生率(P:p = 0.018,B:p = 0.02)和截肢发生率(P:p = 0.009,P:p = 0.012)显著下降。
CLVI中动脉和静脉早期分流的政策已被证明具有极大益处,在显著改善治疗结果、提高手术规范性以及促进相关专家之间的和谐协作方面表现突出。