日本成年人中绿茶与总咖啡因摄入量及自我报告的2型糖尿病风险之间的关系。
The relationship between green tea and total caffeine intake and risk for self-reported type 2 diabetes among Japanese adults.
作者信息
Iso Hiroyasu, Date Chigusa, Wakai Kenji, Fukui Mitsuru, Tamakoshi Akiko
机构信息
Public Health, Department of Social and Environmental Health, Osaka University and Osaka City University, Suita-shi, Osaka, Japan.
出版信息
Ann Intern Med. 2006 Apr 18;144(8):554-62. doi: 10.7326/0003-4819-144-8-200604180-00005.
BACKGROUND
In western populations, coffee consumption is associated with a reduced risk for type 2 diabetes; however, the effect of green, black, and oolong teas is unclear.
OBJECTIVE
To examine the relationship between consumption of these beverages and risk for diabetes.
DESIGN
Retrospective cohort study.
SETTING
25 communities across Japan.
PARTICIPANTS
A total of 17,413 persons (6727 men and 10,686 women; 49% of the original study population) who were 40 to 65 years of age; had no history of type 2 diabetes, cardiovascular disease, or cancer at the baseline lifestyle survey; and completed the 5-year follow-up questionnaire. There was no difference in body mass index levels at baseline between respondents and nonrespondents.
MEASUREMENTS
Questionnaire on consumption of coffee; black, green, and oolong teas; and physician-diagnosed diabetes.
RESULTS
During the 5-year follow-up, there were 444 self-reported new cases of diabetes in 231 men and 213 women (5-year event rates, 3.4% and 2.0%, respectively). Consumption of green tea and coffee was inversely associated with risk for diabetes after adjustment for age, sex, body mass index, and other risk factors. Multivariable odds ratios for diabetes among participants who frequently drank green tea and coffee (> or =6 cups of green tea per day and > or =3 cups of coffee per day) were 0.67 (95% CI, 0.47 to 0.94) and 0.58 (CI, 0.37 to 0.90), respectively, compared with those who drank less than 1 cup per week. No association was found between consumption of black or oolong teas and the risk for diabetes. Total caffeine intake from these beverages was associated with a 33% reduced risk for diabetes. These inverse associations were more pronounced in women and in overweight men.
LIMITATIONS
Diabetes was self-reported, no data were available on consumption of soda, and the follow-up rate was low.
CONCLUSIONS
Consumption of green tea, coffee, and total caffeine was associated with a reduced risk for type 2 diabetes.
背景
在西方人群中，饮用咖啡与2型糖尿病风险降低相关；然而，绿茶、红茶和乌龙茶的影响尚不清楚。
目的
研究饮用这些饮品与糖尿病风险之间的关系。
设计
回顾性队列研究。
地点
日本全国25个社区。
参与者
共有17413人（男性6727人，女性10686人；占原研究人群的49%），年龄在40至65岁之间；在基线生活方式调查时无2型糖尿病、心血管疾病或癌症病史；并完成了5年随访问卷。应答者与未应答者在基线时的体重指数水平无差异。
测量指标
关于咖啡、红茶、绿茶和乌龙茶饮用情况的问卷，以及医生诊断的糖尿病。
结果
在5年随访期间，有444例自我报告的糖尿病新病例，其中男性231例，女性213例（5年事件发生率分别为3.4%和2.0%）。在调整年龄、性别、体重指数和其他风险因素后，饮用绿茶和咖啡与糖尿病风险呈负相关。与每周饮用少于1杯的参与者相比，经常饮用绿茶（每天≥6杯）和咖啡（每天≥3杯）的参与者患糖尿病的多变量比值比分别为0.67（95%CI，0.47至0.94）和0.58（CI，0.37至0.90）。未发现饮用红茶或乌龙茶与糖尿病风险之间存在关联。这些饮品的总咖啡因摄入量与糖尿病风险降低33%相关。这些负相关在女性和超重男性中更为明显。
局限性
糖尿病为自我报告，无汽水饮用数据，且随访率较低。
结论
饮用绿茶、咖啡和总咖啡因与2型糖尿病风险降低相关。
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