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饮茶对糖尿病前期逆转和进展的影响:一项前瞻性队列研究。

The Impact of Tea Consumption on Prediabetes Regression and Progression: A Prospective Cohort Study.

作者信息

Li Tingting, Rayner Christopher K, Horowitz Michael, Jones Karen, Xie Cong, Huang Weikun, Sun Zilin, Qiu Shanhu, Wu Tongzhi

机构信息

Department of Endocrinology, Zhongda Hospital, Institute of Diabetes, School of Medicine, Southeast University, Nanjing 210009, China.

Centre of Research Excellence in Translating Nutritional Science to Good Health, Adelaide Medical School, The University of Adelaide, Adelaide, SA 5000, Australia.

出版信息

Nutrients. 2025 Jul 19;17(14):2366. doi: 10.3390/nu17142366.

DOI:10.3390/nu17142366
PMID:40732991
Abstract

Lifestyle modifications are pivotal to preventing the progression of prediabetes and associated cardiometabolic diseases. Recent evidence from cross-sectional analysis of community-dwelling Chinese adults suggests that regular consumption of tea, particularly dark tea, is associated with a reduced risk of both prediabetes and type 2 diabetes. However, the effects of tea consumption on prediabetes progression and regression remain uncertain. This study investigated the associations of tea consumption with prediabetes progression and regression in Chinese adults with prediabetes. A cohort of 2662 Chinese adults with prediabetes was followed over ~3 years. Baseline tea consumption, including the type (green, black, dark, or other) and frequency (daily, sometimes, or nil), was assessed using standardized questionnaires. Prediabetes was defined according to the American Diabetes Association criteria. Multinomial logistic and linear regression analyses with multivariable adjustment was performed to evaluate associations. Compared to non-tea drinkers, dark tea consumers were less likely to progress to type 2 diabetes (odds ratio [OR]: 0.28, 95% confidence interval [CI]: 0.11, 0.72, = 0.01), whereas green tea consumption was associated with a reduced probability of regressing to normoglycemia (OR: 0.73, 95 CI%: 0.59, 0.90, = 0.01). These findings support further exploration of dark tea consumption as a strategy to reduce prediabetes progression, and suggest that effects of green tea consumption should also be examined more closely in this population.

摘要

生活方式的改变对于预防糖尿病前期及相关心脏代谢疾病的进展至关重要。对居住在社区的中国成年人进行横断面分析的最新证据表明,经常饮茶,尤其是黑茶,与降低糖尿病前期和2型糖尿病的风险有关。然而,饮茶对糖尿病前期进展和逆转的影响仍不确定。本研究调查了中国糖尿病前期成年人饮茶与糖尿病前期进展和逆转之间的关联。对2662名患有糖尿病前期的中国成年人进行了约3年的随访。使用标准化问卷评估基线饮茶情况,包括茶的类型(绿茶、红茶、黑茶或其他)和频率(每天、有时或从不)。糖尿病前期根据美国糖尿病协会标准定义。进行多变量调整的多项逻辑回归和线性回归分析以评估关联。与不饮茶者相比,饮用黑茶的人进展为2型糖尿病的可能性较小(优势比[OR]:0.28,95%置信区间[CI]:0.11,0.72, = 0.01),而饮用绿茶与恢复正常血糖的概率降低有关(OR:0.73,95%CI:0.59,0.90, = 0.01)。这些发现支持进一步探索饮用黑茶作为降低糖尿病前期进展的策略,并表明在该人群中也应更密切地研究饮用绿茶的影响。

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本文引用的文献

1
The association of sweetened beverage intake with risk of type 2 diabetes in an Australian population: A longitudinal study.澳大利亚人群中甜味饮料摄入量与2型糖尿病风险的关联:一项纵向研究。
Diabetes Metab. 2025 May 16:101665. doi: 10.1016/j.diabet.2025.101665.
2
Green Tea Components: In Vitro and In Vivo Evidence for Their Anticancer Potential in Colon Cancer.绿茶成分:其在结肠癌中抗癌潜力的体外和体内证据
Cancers (Basel). 2025 Feb 13;17(4):623. doi: 10.3390/cancers17040623.
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Associations of Diabetes and Prediabetes With Mortality and Life Expectancy in China: A National Study.
中国糖尿病和糖尿病前期与死亡率和预期寿命的关系:一项全国性研究。
Diabetes Care. 2024 Nov 1;47(11):1969-1977. doi: 10.2337/dca24-0012.
4
Dark tea consumption is associated with a reduced risk of dysglycaemia and increased urinary glucose and sodium excretion in Chinese adults.在中国成年人中,饮用黑茶与血糖异常风险降低以及尿糖和尿钠排泄增加有关。
Diabetes Obes Metab. 2024 Oct;26(10):4705-4712. doi: 10.1111/dom.15839. Epub 2024 Aug 7.
5
Association of green tea consumption with prediabetes, diabetes and markers of glucose metabolism in rural Vietnam: a cross-sectional study.越南农村地区绿茶摄入与糖尿病前期、糖尿病及葡萄糖代谢标志物的关系:一项横断面研究。
Br J Nutr. 2024 Jun 14;131(11):1883-1891. doi: 10.1017/S0007114524000412. Epub 2024 Feb 16.
6
Biological potential and mechanisms of Tea's bioactive compounds: An Updated review.茶的生物活性化合物的生物学潜力和机制:最新综述。
J Adv Res. 2024 Nov;65:345-363. doi: 10.1016/j.jare.2023.12.004. Epub 2023 Dec 5.
7
Effects of Key Components on the Antioxidant Activity of Black Tea.关键成分对红茶抗氧化活性的影响
Foods. 2023 Aug 21;12(16):3134. doi: 10.3390/foods12163134.
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State-of-the-art review of theabrownins: from preparation, structural characterization to health-promoting benefits.褐藻糖胶的前沿综述:从制备、结构表征到健康促进益处
Crit Rev Food Sci Nutr. 2024 Nov;64(31):11321-11340. doi: 10.1080/10408398.2023.2236701. Epub 2023 Aug 16.
9
Dark tea: A popular beverage with possible medicinal application.黑茶:一种可能具有药用价值的流行饮品。
Chin Herb Med. 2022 Nov 24;15(1):33-36. doi: 10.1016/j.chmed.2022.08.005. eCollection 2023 Jan.
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Diabetes Obes Metab. 2022 Aug;24(8):1656-1660. doi: 10.1111/dom.14730. Epub 2022 May 25.