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绿茶、其他茶类及咖啡的摄入量与日本男性和女性以慢性肾病为根本病因的死亡风险:JACC研究

Green tea, other teas and coffee consumption and risk of death from chronic kidney disease as the underlying cause among Japanese men and women: the JACC Study.

作者信息

Guo Shuai, Yamagishi Kazumasa, Kihara Tomomi, Muraki Isao, Tamakoshi Akiko, Iso Hiroyasu

机构信息

Doctoral Program in Public Health, Graduate School of Comprehensive Human Sciences, University of Tsukuba.

Department of Public Health Medicine, Institute of Medicine, and Health Services Research and Development Center, University of Tsukuba.

出版信息

Environ Health Prev Med. 2025;30:13. doi: 10.1265/ehpm.24-00291.

Abstract

BACKGROUND

To explore the associations of green tea, coffee, black tea, and oolong tea consumption with mortality from chronic kidney disease (CKD) as the underlying cause among Japanese adults.

METHODS

We conducted a prospective cohort study of 110,585 men and women aged 40-79 years at recruitment from 1986 to 1990. Baseline information on the consumption of tea and coffee, lifestyles, and medical histories was obtained via self-administered questionnaires. We used multivariable Cox regression models to estimate sex-specific hazard ratios and 95% CIs of mortality from CKD associated with the consumption of green tea, coffee, black tea, or oolong tea.

RESULTS

After a median 19-year follow-up, the hazard ratios of mortality from CKD in women were 0.49 (95% CI, 0.22-1.06) for 1-2 cups of green tea per day, 0.56 (0.31-0.99) for 3-4 cups per day, and 0.55 (0.32-0.93) for ≥5 cups per day, compared with <1 cup per day. No such association was found in men. Coffee, black tea, and oolong tea consumption were not associated with CKD risk in either sex.

CONCLUSIONS

Daily consumption of green tea was associated with a lower risk of mortality from CKD in women.

摘要

背景

探讨日本成年人中绿茶、咖啡、红茶和乌龙茶的摄入量与以慢性肾脏病(CKD)为根本死因的死亡率之间的关联。

方法

我们对1986年至1990年招募的110585名年龄在40 - 79岁之间的男性和女性进行了一项前瞻性队列研究。通过自填问卷获取了关于茶和咖啡摄入量、生活方式及病史的基线信息。我们使用多变量Cox回归模型来估计与绿茶、咖啡、红茶或乌龙茶摄入量相关的CKD死亡的性别特异性风险比及95%置信区间。

结果

经过中位数为19年的随访,与每天饮用绿茶少于1杯相比,女性每天饮用1 - 2杯绿茶时CKD死亡的风险比为0.49(95%置信区间,0.22 - 1.06),每天饮用3 - 4杯时为0.56(0.31 - 0.99),每天饮用≥5杯时为0.55(0.32 - 0.93)。在男性中未发现此类关联。咖啡、红茶和乌龙茶的摄入量与任何性别的CKD风险均无关联。

结论

女性每日饮用绿茶与较低的CKD死亡风险相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5198/11925710/552a7ada6aaa/ehpm-30-013-g001.jpg

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