Voytek T M, Ricci A, Cartun R W
Department of Pathology and Laboratory Medicine, Hartford Hospital, Connecticut.
Mod Pathol. 1991 Sep;4(5):582-5.
Primary eccrine carcinoma and metastatic mammary duct carcinoma are histologically similar and histogenetically related neoplasms that may on occasion be mistaken for one another. Mammary duct carcinomas, in primary or metastatic sites, will often express estrogen and progesterone receptors (ER and PR), and these may be detected by either biochemical or immunocytochemical methods. The expression of ER and PR in primary eccrine carcinoma, however, has not been studied. Three eccrine carcinomas were probed with antibodies to ER and PR. Immunoreactivity for hormone receptors was identified in all three cases. The recognition of this immunophenotype may be important in avoiding misdiagnosing receptor-positive eccrine carcinoma as metastatic breast cancer.
原发性小汗腺癌和转移性乳腺导管癌在组织学上相似，且在组织发生学上相关，有时可能会相互误诊。原发性或转移性部位的乳腺导管癌通常会表达雌激素和孕激素受体（ER和PR），可通过生化或免疫细胞化学方法检测到这些受体。然而，原发性小汗腺癌中ER和PR的表达尚未得到研究。用抗ER和PR抗体检测了三例小汗腺癌。在所有三例病例中均发现了激素受体的免疫反应性。认识到这种免疫表型对于避免将受体阳性的小汗腺癌误诊为转移性乳腺癌可能很重要。
