Okuda Shinya, Miyauchi Akira, Oda Takenori, Haku Takamitsu, Yamamoto Tomio, Iwasaki Motoki
Department of Orthopaedic Surgery, Osaka Rosai Hospital, Osaka, Japan.
J Neurosurg Spine. 2006 Apr;4(4):304-9. doi: 10.3171/spi.2006.4.4.304.
Previous studies of surgical complications associated with posterior lumbar interbody fusion (PLIF) are of limited value due to intrastudy variation in instrumentation and fusion techniques. The purpose of the present study was to examine rates of intraoperative and postoperative complications of PLIF using a large number of cases with uniform instrumentation and a uniform fusion technique.
The authors reviewed the hospital records of 251 patients who underwent PLIF for degenerative lumbar disorders between 1996 and 2002 and who could be followed for at least 2 years. Intraoperative, early postoperative, and late postoperative complications were investigated. Intraoperative complications occurred in 26 patients: dural tearing in 19 patients and pedicle screw malposition in seven patients. Intraoperative complications did not affect the postoperative clinical results. Early postoperative complications occurred in 19 patients: brain infarction occurred in one, infection in one, and neurological complications in 17. Of the 17 patients with neurological complications, nine showed severe motor loss such as foot drop; the remaining eight patients showed slight motor loss or radicular pain alone, and their symptoms improved within 6 weeks. Late postoperative complications occurred in 17 patients: hardware failure in three, nonunion in three, and adjacent-segment degeneration in 11. Postoperative progression of symptomatic adjacent-segment degeneration was defined as a condition that required additional surgery to treat neurological deterioration.
The most serious complications of PLIF were postoperative severe neurological deficits and adjacent-segment degeneration. Prevention and management of such complications are necessary to attain good long-term clinical results.
以往关于腰椎后路椎间融合术(PLIF)相关手术并发症的研究,由于研究中器械和融合技术的差异,其价值有限。本研究的目的是使用大量采用统一器械和统一融合技术的病例,来检查PLIF术中及术后并发症的发生率。
作者回顾了1996年至2002年间因退行性腰椎疾病接受PLIF治疗且随访至少2年的251例患者的医院记录。对术中、术后早期和晚期并发症进行了调查。术中并发症发生在26例患者中:19例出现硬脊膜撕裂,7例出现椎弓根螺钉位置不当。术中并发症未影响术后临床结果。术后早期并发症发生在19例患者中:1例发生脑梗死,1例发生感染,17例发生神经并发症。在17例发生神经并发症的患者中,9例出现严重运动功能丧失,如足下垂;其余8例仅表现为轻微运动功能丧失或单纯神经根性疼痛,且其症状在6周内改善。术后晚期并发症发生在17例患者中:3例出现内固定失败,3例出现不融合,11例出现相邻节段退变。有症状的相邻节段退变的术后进展被定义为需要额外手术来治疗神经功能恶化的情况。
PLIF最严重的并发症是术后严重神经功能缺损和相邻节段退变。预防和处理此类并发症对于获得良好的长期临床效果是必要的。