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[细菌肠道微生物群与轮状病毒颗粒相互作用的电子显微镜研究]

[An electron microscopic study of the interaction of bacterial intestinal microflora and rotavirus virions].

作者信息

Shelkovaia N G, Kupchinskiĭ L G, Znamenskiĭ V A, Bondarenko V M

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1991 Sep(9):18-21.

PMID:1661985
Abstract

Transmission electron microscopy has revealed the capacity of rotaviruses for adsorption on Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis cells and the absence of such capacity with respect to Enterococcus faecalis, Lactobacillus casei and Edwardsiella tarda. Different degrees and a varying character of the adsorption of rotaviruses by the representatives of the opportunistic group of bacteria have been established, which may aggravate the course of rotavirus diarrhea due to the aggregation of viral particles. For the first time the phenomenon of the selective destructive adsorption of rotaviruses by E. coli indigenous strains M-17 and 33/29, typical representatives of normal enteric microflora, is described. This observation should be regarded as one of important biological mechanisms responsible for the protection of the body from rotavirus infection.

摘要

透射电子显微镜已揭示轮状病毒吸附于大肠杆菌、肺炎克雷伯菌、奇异变形杆菌细胞的能力,以及其对粪肠球菌、干酪乳杆菌和迟钝爱德华氏菌无此吸附能力。已确定机会性细菌群的代表对轮状病毒的吸附程度不同且性质各异,这可能因病毒颗粒聚集而加重轮状病毒腹泻的病程。首次描述了正常肠道微生物群的典型代表——大肠杆菌本土菌株M - 17和33/29对轮状病毒的选择性破坏性吸附现象。这一观察结果应被视为机体抵御轮状病毒感染的重要生物学机制之一。

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