Mowatt G, Cook J A, Fraser C, McKerrow W S, Burr J M
Health Services Research Unit, University of Aberdeen, Polwarth Building, Foresterhill, UK.
Clin Otolaryngol. 2006 Apr;31(2):95-102. doi: 10.1111/j.1749-4486.2006.01162.x.
In the meta-analysis models, compared with cold steel dissection with ties/packs haemostasis (reference technique): * Bipolar diathermy dissection and haemostasis was associated with statistically significant lower odds of primary haemorrhage (OR 0.13, 95% CrI 0.03 to 0.51), including primary haemorrhage requiring return to theatre (OR 0.002, 95% CrI <0.001 to 0.26). * Coblation was associated with statistically significant higher odds of secondary haemorrhage requiring return to theatre (OR 33.82, 95% CrI 1.25 to 5676.00). * Monopolar and bipolar diathermy dissection and haemostasis (OR 4.12, 95% CrI 1.12 to 14.67; OR 2.86, 95% CrI 1.12 to 8.02, respectively), coblation (OR 3.75, 95% CrI 1.29 to 12.12), and cold steel dissection with monopolar or bipolar diathermy haemostasis (OR 4.83, 95% CrI 1.56 to 15.95; OR 9.18, 95% CrI 3.09 to 30.53, respectively) were all associated with statistically significant higher odds of secondary haemorrhage. * In deciding which technique to employ, factors to consider include patient characteristics, the underlying risk of primary or secondary haemorrhage, which is regarded as likely to be more serious, and the clinical significance of the observed differences in haemorrhage rates across techniques.
在荟萃分析模型中,与采用结扎/填塞止血的冷钢解剖术(参考技术)相比:* 双极电凝解剖和止血与原发性出血的统计学显著较低几率相关(OR 0.13,95% CrI 0.03至0.51),包括需要返回手术室处理的原发性出血(OR 0.002,95% CrI <0.001至0.26)。* 低温等离子消融术与需要返回手术室处理的继发性出血的统计学显著较高几率相关(OR 33.82,95% CrI 1.25至5676.00)。* 单极和双极电凝解剖及止血(分别为OR 4.12,95% CrI 1.12至14.67;OR 2.86,95% CrI 1.12至8.02)、低温等离子消融术(OR 3.75,95% CrI 1.29至12.12)以及采用单极或双极电凝止血的冷钢解剖术(分别为OR 4.83,95% CrI 1.56至15.95;OR 9.18,95% CrI 3.09至30.53)均与继发性出血的统计学显著较高几率相关。* 在决定采用哪种技术时,需要考虑的因素包括患者特征、原发性或继发性出血的潜在风险(哪种风险被认为可能更严重)以及不同技术间观察到的出血率差异的临床意义。