Juutilainen Jukka, Kumlin Timo
Department of Environmental Sciences, University of Kuopio, Kuopio, Finland.
Bioelectromagnetics. 2006 Jul;27(5):423-6. doi: 10.1002/bem.20231.
The evidence of magnetic field (MF) effects on melatonin production in humans is limited and inconsistent. Part of the inconsistencies might be explained by findings suggesting interaction with light in pineal responses to MFs. To test this hypothesis, we reanalyzed data from a previously published study on 6-hydroxy melatonin sulfate (6-OHMS) excretion in women occupationally exposed to extremely low-frequency MFs. Based on questionnaire data on exposure to light-at-night (LAN), and measurement-based MF data, the 60 women were classified to four groups: no MF, no LAN; MF, no LAN; no MF, LAN; MF, LAN. The lowest excretion of 6-OHMS was observed in the group of women who were exposed to both MF and LAN, and the differences between the four groups were significant (P < .0001). The result is based on low numbers, but supports the hypothesis that daytime occupational exposure to MF enhances the effects of nighttime light exposure on melatonin production.
关于磁场（MF）对人体褪黑素分泌影响的证据有限且不一致。部分不一致情况可能由以下研究结果解释，即表明在松果体对磁场的反应中与光存在相互作用。为验证这一假设，我们重新分析了之前发表的一项关于职业性暴露于极低频磁场的女性尿硫酸6 - 羟基褪黑素（6 - OHMS）排泄情况的研究数据。根据夜间光照（LAN）暴露的问卷调查数据以及基于测量的磁场数据，将60名女性分为四组：无磁场，无夜间光照；有磁场，无夜间光照；无磁场，有夜间光照；有磁场，有夜间光照。在同时暴露于磁场和夜间光照的女性组中观察到6 - OHMS排泄量最低，且四组之间的差异具有显著性（P <.0001）。该结果基于样本数量较少的数据，但支持以下假设：白天职业性暴露于磁场会增强夜间光照对褪黑素分泌的影响。
