Feller Liviu, Wood Neil H, Raubenheimer Erich J
Periodontology and Oral Medicine, Medical University of Southern Africa, South Africa.
J Int Acad Periodontol. 2006 Apr;8(2):67-70.
Proliferative verrucous leukoplakia (PVL) is a multi-focal oral pre-malignant lesion, proliferative in nature, with a tendency to recur despite adequate therapy, and a high rate of malignant transformation. The field cancerization phenomenon may explain the characteristic behaviour of PVL. A case of PVL is presented and the field cancerization concept is discussed.
增殖性疣状白斑（PVL）是一种多灶性口腔癌前病变，本质上具有增殖性，尽管进行了充分治疗仍有复发倾向，且恶变率高。场癌化现象可能解释了PVL的特征性行为。本文报告了1例PVL病例，并讨论了场癌化概念。
