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腹主动脉瘤

Abdominal aortic aneurysm.

作者信息

Upchurch Gilbert R, Schaub Timothy A

机构信息

University of Michigan Health System, Ann Arbor 48109-0329, USA.

出版信息

Am Fam Physician. 2006 Apr 1;73(7):1198-204.

PMID:16623206
Abstract

Most abdominal aortic aneurysms (AAAs) are asymptomatic, not detectable on physical examination, and silent until discovered during radiologic testing for other reasons. Tobacco use, hypertension, a family history of AAA, and male sex are clinical risk factors for the development of an aneurysm. Ultrasound, the preferred method of screening, is cost-effective in high-risk patients. Repair is indicated when the aneurysm becomes greater than 5.5 cm in diameter or grows more than 0.6 to 0.8 cm per year. Asymptomatic patients with an AAA should be medically optimized before repair, including institution of beta blockade. Symptomatic aneurysms present with back, abdominal, buttock, groin, testicular, or leg pain and require urgent surgical attention. Rupture of an AAA involves complete loss of aortic wall integrity and is a surgical emergency requiring immediate repair. The mortality rate approaches 90 percent if rupture occurs outside the hospital. Although open surgical repair has been performed safely, an endovascular approach is used in select patients if the aortic and iliac anatomy are amenable. Two large randomized controlled trials did not find any improvement in mortality rate or morbidity with this approach compared with conventional open surgical repair.

摘要

大多数腹主动脉瘤(AAA)无症状,体格检查无法检测到,在因其他原因进行放射学检查之前一直未被发现。吸烟、高血压、AAA家族史和男性是动脉瘤形成的临床危险因素。超声是首选的筛查方法,对高危患者具有成本效益。当动脉瘤直径大于5.5厘米或每年增长超过0.6至0.8厘米时,建议进行修复。无症状的AAA患者在修复前应进行医学优化,包括使用β受体阻滞剂。有症状的动脉瘤表现为背部、腹部、臀部、腹股沟、睾丸或腿部疼痛,需要紧急手术治疗。AAA破裂涉及主动脉壁完整性完全丧失,是一种需要立即修复的外科急症。如果在医院外发生破裂,死亡率接近90%。尽管开放手术修复已安全进行,但如果主动脉和髂部解剖结构合适,部分患者可采用血管内治疗方法。两项大型随机对照试验发现,与传统开放手术修复相比,这种方法在死亡率或发病率方面没有任何改善。

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