Todorović Tatjana, Dozić Ivan, Pavlica Dusan, Marković Dejan, Brajović Gavrilo, Ivanović Mirjana, Stevanović Gordana, Mirković Silvija, Andjelski Biljana
Srp Arh Celok Lek. 2005 Jul-Aug;133(7-8):372-8. doi: 10.2298/sarh0508372t.
Saliva is a secretion of the salivary and mucous glands and is of major importance in the maintainance of oral health. Over the last few decades, saliva has been evaluated as a diagnostic fluid in medicine for determining systemic disease markers as well as for monitoring numerous drugs, narcotics, and hormones. The biochemical analysis of saliva is particularly important in dentistry. The estimation of the risk of appearance and diagnosis of disease, monitoring of disease progression, evaluation of therapy efficacy for caries, periodontitis, premalignant and malignant oral lesions, as well as infectious diseases of the oral cavity, can be assessed by analysing different constituents of saliva. Individuals at risk of caries can be identified using tests that determine saliva flow rate, saliva buffer capacity, and colonisation of the oral cavity by cariogenic bacteria. Today, these rapid and simple diagnostic tests are used routinely in caries risk determination. The study and use of saliva-based diagnostics have increased over the last few decades. Clinical testing of saliva shows much promise. However, there is a need for much additional research in this area, before the true clinical value of saliva as a diagnostic fluid in dentistry can be determined.
唾液是唾液腺和黏液腺的分泌物，对维持口腔健康至关重要。在过去几十年里，唾液已被评估为医学上一种用于确定全身疾病标志物以及监测多种药物、麻醉品和激素的诊断液。唾液的生化分析在牙科领域尤为重要。通过分析唾液的不同成分，可以评估疾病出现和诊断的风险、监测疾病进展、评估龋齿、牙周炎、口腔癌前病变和恶性病变以及口腔传染病的治疗效果。可以使用测定唾液流速、唾液缓冲能力以及致龋菌在口腔中定植情况的测试来识别有龋齿风险的个体。如今，这些快速简单的诊断测试在龋齿风险测定中被常规使用。在过去几十年里，基于唾液的诊断方法的研究和应用有所增加。唾液的临床检测显示出很大的前景。然而，在确定唾液作为牙科诊断液的真正临床价值之前，该领域还需要进行大量的额外研究。
